Sodium Butyrate SDS, MSDS Sheet

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Sodium Butyrate SDS Safety Data Sheet
MSDS Sheet, Material Safety Data Sheet 05-Dec-20

Product Name & Other Names: Sodium butyrate; Sodium butanoate; Butyric acid sodium salt.
CAS No.: 156-54-7
EINECS EC Number: 205-857-6
Molecular Weight: 110.09
Chemical Formula: CH3CH2CH2COOHNa
Relevant uses and uses advised against (if any): Industrial Manufacturing.
Suppliers: As per letterhead.

GHS, Globally Harmonized System Classification in accordance with 29 CFR 1910
Classification according to Regulation (EC) No 1272/2008

Skin corrosion/irritation Category 2, H315
Serious eye damage/eye irritation Category 2A, H319
Specific target organ toxicity, single exposure; Respiratory tract irritation Category 3, H335
Germ cell mutagenicity Category 2, H341

Hazard statements:
H315 Causes skin irritation.
H319 Causes serious eye irritation.
H335 May cause respiratory irritation.
H341 Suspected of causing genetic defects.

Precautionary statements:
P202: Do not handle until all safety precautions have been read and understood.
P261: Avoid breathing dust/fume/gas/mist/vapors/spray.
P264: Wash … thoroughly after handling.
P280: Wear protective gloves/protective clothing/eye protection/face protection.
P281: Use personal protective equipment as required.
P302+P352 - IF ON SKIN: Wash with plenty of soap and water.
P303+P361+P353 - IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower.
P332+313: If skin irritation occurs: Get medical advice/attention.
P304 + P340 - IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P305 + P351 + P338 - IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P308+313: IF exposed or concerned: Get medical advice/attention.
P337+313: If eye irritation persists get medical advice/attention.
P405: Store locked up.
P501: Dispose of contents/container in accordance with local/regional/national/international regulations.

Classification according to EU Directives 67/548/EEC or 1999/45/EC:
Hazard Symbol:
Xi Irritant.
Risk Phrases:
R36/37/38 = Irritating to eyes, respiratory system, and skin.
R46 May cause inheritable genetic damage.

Product Name & Other Names: Sodium butyrate; Sodium butanoate; Butyric acid sodium salt.
CAS No.: 156-54-7
EINECS EC Number: 205-857-6

Inhalation: If Sodium Butyrate is inhaled, remove to fresh air. If breathing is difficult, give oxygen. Get medical attention.
Ingestion: Give large amounts of water to drink. Never give anything by mouth to an unconscious person. Get medical attention.
Skin Contact: In case of contact, immediately flush skin with plenty of water. Cover the irritated skin with an emollient. Remove contaminated clothing and shoes. Cold water may be used. Wash clothing & Shoes before reuse. Get medical attention.
Eye Contact: Check for and remove any contact lenses. In case of contact, immediately flush eyes with plenty of water for at least 15 minutes. Cold water may be used. Get medical attention.

Fire: Not expected to be a fire hazard. However, it can burn at higher temperature.
Explosion: No information found.
Fire Extinguishing Media: Use any means suitable for extinguishing surrounding fire.
Special Information: In the event of a fire, wear full protective clothing and NIOSH-approved self-contained breathing apparatus with full face piece operated in the pressure demand or other positive pressure mode. At high temperatures under fire conditions, it may produce toxic or irritating fumes. Fire-extinguishing work is done from the windward and the suitable fire-extinguishing method according to the surrounding situation is used. Uninvolved persons should evacuate to a safe place.

Personal precautions, protective equipment, and emergency procedures: Ventilate area of leak or spill. Avoid breathing dust/fumes/gas/mist/vapors/spray. Use individual protective equipment (waterproof boots, suitable protective clothing, safety glasses, etc.). Restrict unprotected personnel from the area. Prevent any contact with hot surfaces. Do not approach facing the wind. Do not touch the spilled material.
Environmental precautions: Do not let the product enter drains, soil, or water sources.
Methods and materials used for containment Cleanup procedures and Storage:
Small Spill: Use appropriate tools to put the spilled solid in a convenient waste disposal container. Finish cleaning by spreading water on the contaminated surface and dispose of according to legal requirements.
Large Spill: Contain spilled material. Cover with an inert, non-combustible absorbent material, (e.g. sand, earth, diatomaceous earth, vermiculite). Use a shovel to put the material into a convenient waste disposal container. Finish cleaning by spreading water.

Precautions for safe handling: Apply according to good manufacturing and industrial hygiene practices. Ensure proper ventilation. Wash thoroughly after handling. Do not drink, eat, or smoke while handling. Avoid contact with skin, eyes, and clothing. Minimize dust generation. Avoid breathing dust/fumes/gas/mist/vapors/spray. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation. Use individual protective equipment (waterproof boots, suitable protective clothing, safety glasses, etc.). Prevent any contact with hot surfaces.
Conditions for safe storage, including any incompatibilities: Store in cool, dry, and ventilated area away from heat sources and protected from sunlight in tightly closed original container. Keep air contact to a minimum. Store protected from heat, sparks and ignition sources and incompatible materials. Avoid contact with skin and eyes. Avoid inhalation of dust/mist/vapor. Do not store with incompatible materials like strong oxidizing agents and strong acids and strong oxidizing agents.

Airborne Exposure Limits: None established.
Ventilation System: A system of local and/or general exhaust is recommended to keep employee exposures as low as possible. Local exhaust ventilation is generally preferred because it can control the emissions of the contaminant at its source, preventing dispersion of it into the general work area.
Personal Respirators (NIOSH Approved): For conditions of use where exposure to the substance is apparent, consult an industrial hygienist. For emergencies, or instances where the exposure levels are not known, use a full-face piece positive-pressure, air-supplied respirator. WARNING: Air purifying respirators do not protect workers in oxygen-deficient atmospheres.
Skin Protection: Wear impervious protective clothing, including boots, gloves, lab coat, apron or coveralls, as appropriate, to prevent skin contact.
Eye Protection: Use chemical safety goggles and/or a full face shield where splashing is possible. Maintain eye wash fountain and quick-drench facilities in work area.
Other Control Measures: Maintain good housekeeping in work area. Dust deposits on floors and other surfaces may pick up moisture and cause the surfaces to become slippery and present safety hazards. Handle in accordance with good industrial hygiene and safety practice. Wash hands after handling.

Appearance: White to off-white powder.
Odor: Light odor.
Odor threshold: Not available.
pH: Not available.
Relative density: around 0.96
Melting point/freezing point: Not available.
Initial boiling point and boiling range: Not available.
Flash point: Not available.
Auto-ignition temperature: Not available.
Decomposition temperature: Not available.
Upper/lower flammability or explosive limits: Not available.
Vapor pressure: Not available.
Vapor density: Not available.
Evaporation rate: Not available.
Flammability (solid, gas): Not available.
Partition coefficient: n-octanol/water: Not available.
Solubility: Appreciable solubility in water.
Viscosity: Not available.
Molecular Weight: 110.09
Chemical Formula: CH3CH2CH2COOHNa

Stability: Stable under ordinary conditions of use and storage.
Hazardous Decomposition Products: Carbon dioxide and carbon monoxide may form when heated to decomposition. Toxic fumes of the contained metal may be released when heated to decomposition.
Hazardous Polymerization: Will not occur.
Incompatibilities: Strong acids and strong oxidizing agents.
Conditions to Avoid: Incompatibles.

Toxicity to Animals: Not available.
Carcinogenic Effects: Not a reported carcinogen by IARC NTP ACGIH OSHA.
Mutagenic Effects: Classified POSSIBLE for human.
Teratogenic Effects: Not available.
Developmental Toxicity: Not available.

Toxicity to fish: LC50 - Lepomis macrochirus - 5.000 mg/l - 24 h
Toxicity to daphnia & other aquatic invertebrates: EC50 - Daphnia magna (Water flea) - 1.950 mg/l - 24 h
Results of PBT and vPvB assessment: This substance/mixture contains no components considered to be either persistent, bioaccumulative and toxic (PBT), or very persistent and very bioaccumulative (vPvB) at levels of 0.1% or higher.

Whatever cannot be saved for recovery or recycling should be managed in an appropriate and approved waste disposal facility. Processing use or contamination of this product may change the waste management options. State and local disposal regulations may differ from federal disposal regulations. Dispose of container and unused contents in accordance with federal, state, and local requirements.

DOT USA, TDG Canada & ADR/RID Europe: Not regulated.
IMDG/IMO: Not regulated.
IATA/ICAO: Not regulated.

USA:
SARA 302: Butyric Acid, Sodium Salt (156-54-7) – No
SARA 313: Butyric Acid, Sodium Salt (156-54-7) - No
SARA 311/312: Acute health hazard. See section 2.

European Labeling in Accordance with EC Directives:
H315 = Causes skin irritation.
H319 = Causes serious eye irritation.
H335 = May cause respiratory irritation.
H341 = Suspected of causing genetic defects.

DISCLAIMER: The information and recommendations set forth herein (hereinafter "Information") are presented in good faith and believed correct as of the date hereof. It is compiled from various sources and it is not necessarily all inclusive nor fully adequate in every circumstance. In addition, these suggestions should not be confused with nor followed in violation of applicable laws, regulations, rules or insurance requirements applicable. This MSDS sheet is intended only as a guide to the appropriate precautionary handling of the material by a properly trained person using this product. Individuals receiving the information must exercise their independent judgment in determining its appropriateness for a particular purpose.

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