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Mubychem Group, established in 1976, is the pioneer manufacturer of Zinc Chloride, Ammonium Chloride, Calcium Chloride, Potassium Chloride, Sodium Acetate, Sodium Thiosulphate, Magnesium Carbonate, Pharmaceutical, Fragrance & Flavor chemicals in India. Mubychem Group has several manufacturing facilities spread across Western India.
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Magnesium Carbonate BP, Magnesium Carbonate USP.. Magnesium Carbonate Manufacturers Anhydrous CAS No.: 546-93-0, Molecular Weight: 84.31, Chemical Formula: MgCO3
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Heavy Magnesium Carbonate BP
Action and use
Antacid; osmotic laxative.DEFINITION
Hydrated basic magnesium carbonate.
Content
40.0 per cent to 45.0 per cent, calculated as MgO.CHARACTERS
Appearance
White or almost white powder.
Solubility
Practically insoluble in water. It dissolves in dilute acids with effervescence.IDENTIFICATION
A. Bulk density: minimum 0.25 g/ml.
B. It gives the reaction of carbonates.
C. Dissolve about 15 mg in 2 ml of dilute nitric acid and neutralize with dilute sodium hydroxide solution. The solution gives the reaction of magnesium.TESTS
Solution S
Dissolve 5.0 g in 100 ml of dilute acetic acid R. When the effervescence has ceased, boil for 2 min, allow to cool and dilute to 100 ml with dilute acetic acid. Filter, if necessary, through a previously ignited and tarred porcelain or silica filter crucible of suitable porosity to give a clear filtrate.
Appearance of solution
Solution S is not more intensely coloured than reference solution.
Soluble substances
Maximum 1.0 per cent.
Mix 2.00 g with 100 ml of water and boil for 5 min. Filter whilst hot through a sintered-glass filter, allow to cool and dilute to 100 ml with Evaporate 50 ml of the filtrate to dryness and dry at 100-105 °C. The residue weighs not more than 10 mg.
Substances insoluble in acetic acid
Maximum 0.05 per cent.
Any residue obtained during the preparation of solution S, washed, dried, and ignited at 600 ± 50°C, weighs not more than 2.5 mg.
Chlorides
Maximum 700 ppm.
Sulphates
Maximum 0.6 per cent.
Arsenic
Maximum 2 ppm, determined on 10 ml of solution S.
Calcium
Maximum 0.75 per cent.
Iron
Maximum 400 ppm.
Heavy metals
Maximum 20 ppm.FUNCTIONALITY-RELATED CHARACTERISTICS
This section is a non-mandatory part of the monograph and it is not necessary to verify the characteristics to demonstrate compliance.
---Particle-size distribution.
---Bulk and tapped density.
Magnesium Carbonate USP
Magnesium Carbonate USP
Carbonic acid, magnesium salt, basic; or, Carbonic acid, magnesium salt (1:1), hydrate Magnesium carbonate, basic; or, Magnesium carbonate (1:1) hydrate [23389-33-5]. Anhydrous 84.31 [546-93-0].
Magnesium Carbonate is a basic hydrated MgCO3 or a normal hydrated MgCO3. It contains the equivalent of not less than 40.0 percent and not more than 43.5 percent of magnesium oxide (MgO).
Identification When treated with 3 N hydrochloric acid, it dissolves with effervescence, and the resulting solution responds to the tests for Magnesium.
Microbial limits It meets the requirements of the test for absence of Escherichia coli.
Soluble salts Mix 2.0 g with 100 mL of a mixture of equal volumes of n-propyl alcohol and water. Heat the mixture to the boiling point with constant stirring, cool to room temperature, dilute with water to 100 mL, and filter. Evaporate 50 mL of the filtrate on a steam bath to dryness, and dry at 105 for 1 hour: the weight of the residue does not exceed 10 mg (1.0%).
Acid-insoluble substances Mix 5.0 g with 75 mL of water, add hydrochloric acid in small portions, with agitation, until no more of the material dissolves, and boil for 5 minutes. If an insoluble residue remains, filter, wash well with water until the last washing is free from chloride, and ignite: the weight of the ignited residue does not exceed 2.5 mg (0.05%).
Arsenic The limit is 4 ppm.
Limit of calcium : the limit is 0.45%.
Heavy metals: the limit is 0.003%.
Iron: the limit is 0.02%.
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