Chloroform or Trichloromethane Analytical Reagent Grade Manufacturers, with SDS GHS MSDS Sheet |
Supplier, Manufacturer, Exporter of Chloroform or Trichloromethane, Muby Chemicals of Mubychem Group, established in 1976, is the original manufacturers of Specialty Chemicals, Pharmaceutical Excipient, Fragrance Food & Flavor chemicals, Reagent Grade Chemicals, Shale Gas Fracturing Chemicals in India. Mubychem Group has several manufacturing facilities spread across Western India and world wide contacts and toll manufacturers. We are exporting globally to countries like USA, Canada, Europe, UAE, South Africa, Tanzania, Kenya, Egypt, Nigeria, Cameroon, Uganda, Turkey, Mexico, Brazil, Chile, Argentina, Dubai, Korea, Vietnam, Thailand, Malaysia, Indonesia, Australia, China, Germany, France, Italy, Portugal, Bangladesh, etc. The products are offered as per required specifications and in correct shape and size in mm or meshs or microns as specified by the buyer. The participating units have one or more accreditations like FDA - cGMP and GLP approval, ISO-9001 Certified, "REACH" Registered, ISO-14001, ISO/IEC 17025, ISO-22000, FSSC 22000, ISO 45001, Kosher Certified, Halal Certified, HACCP, FSSAI. We offer Commercial Pure & IP BP EP Ph Eur USP NF JP FCC Food Grade Analytical Reagent Grades of Chemicals |
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Chloroform or Trichloromethane: CAS Number: 67-66-3, EINECS EC Number: 200-663-8, Molecular Formula: CHCl3, Molecular Weight: 119.37, HS Code ---**
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SDS MSDS Sheet of Chloroform or Trichloromethane Manufacturers
Chloroform or Trichloromethane
Analytical Reagent Grade Pure Suppliers
Chloroform, or trichloromethane, is an organic compound with formula CHCl3. It is a colorless, sweet-smelling, dense liquid that is produced on a large scale as a precursor to PTFE. It is also a precursor to various refrigerants. It is a powerful anesthetic, euphoriant, anxiolytic and sedative when inhaled or ingested. Chloroform is a colorless, volatile, liquid derivative of trichloromethane with an ether-like odor. Formerly used as an inhaled anesthetic during surgery, the primary use of chloroform today is in industry, where it is used as a solvent and in the production of the refrigerant freon.
Chloroform Analytical Reagent Grade Specifications:
Trichloromethane
CHCl3 --- Formula Wt 119.38
CAS Number 67-66-3
Suitable for use in high-performance liquid chromatography, extraction-concentration analysis, ultraviolet spectrophotometry, or general use. Product labeling shall designate the one or more of these uses for which suitability is represented on the basis of meeting the relevant requirements and tests. The ultraviolet spectrophotometry and liquid chromatography suitability requirements include all of the requirements for general use. The extraction-concentration suitability requirements include only the general use requirement for color.
NOTE. Chloroform should be supplied and stored in amber glass containers and protected from direct sunlight. This solvent usually contains additives to retard decomposition. Typical additives include alcohol or mixed amylenes. The substances darkened by sulfuric acid test is not required for chloroform containing mixed amylenes.
REQUIREMENTS
General Use
Assay: 99.8% CHCl3
MAXIMUM ALLOWABLE
Color (APHA) 10
Residue after evaporation: 0.001%
Acetone and aldehyde: Passes test
Acid and chloride: Passes test
Free chlorine (Cl): Passes test
Lead (Pb): 0.05 ppm
Substances darkened by sulfuric acid: Passes test
Suitability for use in dithizone tests: Passes test.
Chloroform is no longer in the current BP Ph Eur and USP grade specifications monographs.
We also manufacture and supply as under:
tert-Butyldimethylsilyl chloride.
Manufacturers:
MUBY CHEMICALS
Ambernath Mumbai, Ankleshwar Gujarat, India
TEL: (OFFICE) +912223770100, +912223726950
Current Date Time in India GMT+5:30
e-mail: info@mubychem.com
USA, Canada, Mexico and other American
neighbouring buyers may
e-mail: us@mubychem.com
Call toll-free 1-877-682-9243 (1-877-MUBYCHEM)
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Last
18 April, 2024
Exporters to USA Canada UAE Europe South Africa Tanzania Kenya Uganda Egypt Nigeria Turkey Mexico Brazil Argentina Chile Dubai etc.
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Chloroform or Trichloromethane SDS, Safety Data Sheet
MSDS Sheet, Material Safety Data Sheet 09-Oct-20
Section 1: Product and Company Identification
Product Name & Other Names: Chloroform or Trichloromethane.
CAS No.: 67-66-3
EINECS, EC Number: 200-663-8
Molecular Weight: 119.37
Chemical Formula: CHCl3
Identified uses: Laboratory chemicals, Manufacture of substances
Supplier: As per letterhead.
Section 2: Hazards Identification
GHS, Globally Harmonized System Classification in accordance with 29 CFR 1910
Classification according to Regulation (EC) No 1272/2008
Acute toxicity, Oral (Category 4), H302
Skin irritation (Category 2), H315
Eye irritation (Category 2), H319
Acute toxicity, Inhalation (Category 3), H331
Specific target organ toxicity - single exposure (Category 3), Central nervous system, H336
Carcinogenicity (Category 2), H351
Reproductive toxicity (Category 2), H361d
Specific target organ toxicity - repeated exposure (Category 1), H372
Labeling according to GHS & Regulation (EC) No 1272/2008
GHS Label Elements  Toxic |
GHS Label Elements |
Signal Words: Danger
Hazard statements:
H302: Harmful if swallowed.
H315: Causes skin irritation.
H319: Causes serious eye irritation.
H331: Toxic if inhaled.
H336: May cause drowsiness or dizziness.
H351: Suspected of causing cancer.
H361d: Suspected of damaging the unborn child.
H372: Causes damage to organs through prolonged or repeated exposure.
Precautionary statements:
P202: Do not handle until all safety precautions have been read and understood.
P260: Do not breathe dust/fume/gas/mist/vapors/spray.
P264 Wash thoroughly after handling.
P270: Do not eat, drink or smoke when using this product.
P271: Use only outdoors or in a well-ventilated area.
P273: Avoid release to the environment.
P280: Wear protective gloves/protective clothing/eye protection/face protection.
P285: In case of inadequate ventilation wear respiratory protection.
P330 : Rinse mouth
P301+P312: IF SWALLOWED: Call a POISON CENTER or doctor/ physician if you feel unwell.
P302+P352: IF ON SKIN: Wash with plenty of soap and water.
P304+341: IF INHALED: If breathing is difficult, remove victim to fresh air and keep at rest in a position comfortable for breathing.
P305+P351+P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P308+313: IF exposed or concerned: Get medical advice/attention.
P337+313: If eye irritation persists get medical advice/attention.
P342+311: If experiencing respiratory symptoms: Call a POISON CENTER or doctor/physician.
Classification according to EU Directives 67/548/EEC or 1999/45/EC:
Hazard Symbols:
T Toxic
Xn Harmful
Xi Irritant
Risk Phrases:
R22 Harmful if swallowed.
R23 Toxic by inhalation.
R36/38 Irritating to eyes and skin.
R45 May cause cancer
R48 Danger of serious damage to health by prolonged exposure
R61 May cause harm to the unborn child.
R67 Vapors may cause drowsiness and dizziness.
Section 3: Composition / Information on Ingredients
Product Name & Other Names: Chloroform or Trichloromethane.
CAS No.: 67-66-3
EINECS, EC Number: 200-663-8
Section 4: First Aid Measures
Always seek medical attention after first aid measures are provided.
Eyes: Immediately flush eyes with excess water for 15 minutes, lifting lower and upper eyelids occasionally.
Skin: Immediately flush skin with excess water for 15 minutes while removing contaminated clothing.
Ingestion: Call Emergency Medical immediately. Rinse mouth with cold water. Give victim 1-2 cups of water or milk to drink. Induce vomiting immediately.
Inhalation: Remove to fresh air. If not breathing, give artificial respiration.
Section 5: Fire Fighting Measures
When heated to decomposition, emits fumes. Avoid contamination with oxidizing agents and ignition source.
Protective equipment and precautions for firefighters: Firefighters should wear full fire fighting turn-out gear and respiratory protection. Cool container with water spray.
Special hazards arising from the substance: Carbon oxides, Hydrogen chloride and Toxic fumes.
Suitable fire fighting medium: Use water spray, dry sand, foam or dry chemical or carbon dioxide to extinguish fire. Use water spray to cool unopened containers.
Special Information: In the event of a fire, wear full protective clothing and NIOSH-approved self-contained breathing apparatus with full face piece operated in the pressure demand or other positive pressure mode. At high temperatures under fire conditions, it may produce toxic or irritating fumes.
Section 6: Accidental Release Measures
Ensure adequate ventilation. Evacuate personnel to safe areas. Keep up-wind. Close doors and windows of adjacent premises. Use personal protection. Isolate the hazard area and deny entry to unnecessary and unprotected personnel. Prevent further leakage or spillage if safe to do so.
Personal precautions, protective equipment, and emergency procedures: Avoid breathing dust/fumes/gas/mist/vapors/spray. Use individual protective equipment (waterproof boots, suitable protective clothing, safety glasses, etc.). Restrict unprotected personnel from the area. Prevent any contact with hot surfaces. Do not approach facing the wind. Do not touch the spilled material.
Environmental precautions: Do not let the product enter drains, soil, or water sources.
Methods and materials used for containment Cleanup procedures and Storage: Do not inhale dust, vapors, mist, or gas. Avoid dust formation. Contain spilled material. Cover with an inert, non-combustible absorbent material, (e.g. sand, earth, diatomaceous earth, vermiculite). Use a shovel to put the material into a convenient waste disposal container. Finish cleaning by spreading water on the contaminated surface and allow to evacuate as per law.
Section 7: Handling and Storage Green
Precautions for safe handling: Apply according to good manufacturing and industrial hygiene practices. Ensure proper ventilation. In case of insufficient ventilation, wear suitable respiratory equipment. Wash thoroughly after handling. Do not drink, eat, or smoke while handling. Avoid contact with skin, eyes, and clothing. Minimize dust generation. Avoid breathing dust/fumes/gas/mist/vapors/spray. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation. Use individual protective equipment (waterproof boots, suitable protective clothing, safety glasses, etc.). Prevent any contact with hot surfaces.
Conditions for safe storage, including any incompatibilities: Store in cool, dry, and ventilated area away from heat sources and protected from sunlight in tightly closed original container. Keep air contact to a minimum. Store protected from heat, sparks and ignition sources and incompatible materials. Avoid contact with skin and eyes. Avoid inhalation of dust/mist/vapor. Do not store with incompatible materials like strong oxidizing agents, strong bases, Magnesium, sodium/sodium oxides, lithium.
Section 8: Exposure Controls / Personal Protection
Use ventilation to keep airborne concentrations below exposure limits. Have approved eyewash facility, safety shower, and fire extinguishers readily available. Wear chemical splash goggles and chemical resistant clothing such as gloves and aprons. Wash hands thoroughly after handling material and before eating or drinking. Use NIOSH-approved respirator with a dust cartridge.
Exposure guidelines:
ACGIH TWA (ppm): 10 ppm (Chloroform; USA; Time-weighted average exposure limit 8 h; TLV - Adopted Value) .
Respiratory Protection: Recommended respirators are NIOSH-approved N95 or CEN-approved FFP2 particulate respirators. These are to be only used as a backup to local exhaust ventilation or other engineering controls. If the respirator is the only means of protection, a full-face supplied air respirator must be used.
Ventilation System: A system of local and/or general exhaust is recommended to keep employee exposures as low as possible. Local exhaust ventilation is generally preferred because it can control the emissions of the contaminant at its source, preventing dispersion of it into the general work area.
Personal Respirators (NIOSH Approved): For conditions of use where exposure to dust or mist is apparent and engineering controls are not feasible, a particulate respirator may be worn. For emergencies or instances where the exposure levels are not known, use a full-face positive-pressure, air-supplied respirator.
Skin Protection: Wear protective gloves and clean body-covering clothing.
Eye Protection: Use chemical safety goggles and/or full face shield where dusting or splashing of solutions is possible. Maintain eye wash fountain and quick-drench facilities in work area.
Other Control Measures: Maintain good housekeeping in work area. Dust deposits on floors and other surfaces may pick up moisture and cause the surfaces to become slippery and present safety hazards. Handle in accordance with good industrial hygiene and safety practice. Wash hands after handling.
Section 9: Physical and Chemical Properties
Physical state and appearance: Clear colorless liquid.
Odor: Sweet.
Odor threshold: Not available.
pH: Not available.
Relative density: about 1.5
Boiling Point: 60.5 to 61.5.
Melting Point: -63C literature.
Flash point: Not available.
Auto-ignition temperature: Not available.
Decomposition temperature: Not available.
Upper/lower flammability or explosive limits: Not available.
Vapor pressure: Not available.
Vapor density: Not available.
Evaporation rate: Not available.
Flammability (solid, gas): Not available.
Partition coefficient: n-octanol/water: Not available.
Solubility: Slightly soluble in water.
Viscosity: Not available.
Molecular Weight: 119.37
Chemical Formula: CHCl3
Section 10: Stability and Reactivity
Avoid heat and ignition sources.
Stability: Stable under normal conditions of use and storage.
Incompatibility: Heat, Light, Strong oxidizing agents, Strong bases, Magnesium, Sodium/sodium oxides, Lithium.
Hazardous Decomposition Products: Carbon oxides, Hydrogen chloride and Toxic fumes.
Hazardous Polymerization: Has not been reported.
Section 11: Toxicology Information
LD50 Oral, Rat: 908 mg/kg.
LD50 Dermal, Rabbit: > 20,000 mg/kg
Carcinogenicity: IARC: 2B - Group 2B: Possibly carcinogenic to humans.
Reproductive toxicity: Suspected of damaging the unborn child. Suspected human reproductive toxicant.
Germ cell mutagenicity: Laboratory experiments have shown mutagenic effects.
Section 12: Ecological Information
Toxicity to fish:
LC50 - Leuciscus idus (Golden orfe) - 162 mg/l - 48 h.
LC100 - Leuciscus idus (Golden orfe) - 220 mg/l - 48 h.
Toxicity to daphnia and other aquatic invertebrates: EC50 - Daphnia magna (Water flea) - 79.00 mg/l - 24 h.
Persistence and degradability: No data available.
Results of PBT and vPvB assessment: No data available.
Mobility in soil: No data available.
Section 13: Disposal Considerations
Check with all applicable local, regional, and national laws and regulations.
Section 14: Transport Information
DOT USA and ADR/RID Europe:
UN-No: UN1888
Proper Shipping Name: Chloroform.
Hazard Class: 6.1; Packing Group: III
TDG:
UN-No: UN1888
Proper Shipping Name: Chloroform.
Hazard Class: 6.1; Packing Group: III
IATA
UN-No: UN1888
Proper Shipping Name: Chloroform.
Hazard Class: 6.1; Packing Group: III
IMDG/IMO
UN-No: UN1888
Proper Shipping Name: Chloroform.
Hazard Class: 6.1; Packing Group: III
Section 15: Regulatory Information
USA:
SARA 311/312 Hazard Categories: Acute Health Hazard, Chronic Health Hazard
California Proposition 65: This product contains a chemical known to the State of California to cause cancer and development toxicity.
Section 16: Other Information
European Labeling in Accordance with EC Directives:
H302: Harmful if swallowed.
H315: Causes skin irritation.
H319: Causes serious eye irritation.
H331: Toxic if inhaled.
H336: May cause drowsiness or dizziness.
H351: Suspected of causing cancer.
H361d: Suspected of damaging the unborn child.
H372 Causes damage to organs through prolonged or repeated exposure.
Classification according to EU Directives 67/548/EEC or 1999/45/EC:
Hazard Symbols:
T Toxic
Xn Harmful
Xi Irritant
Risk Phrases:
R22 Harmful if swallowed.
R23 Toxic by inhalation.
R36/38 Irritating to eyes and skin.
R45 May cause cancer
R48 Danger of serious damage to health by prolonged exposure
R61 May cause harm to the unborn child.
R67 Vapors may cause drowsiness and dizziness.
Disclaimer:
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Our company provides this MSDS sheet in good faith but makes no representation as to its comprehensiveness or accuracy. This SDS sheet is intended only as a guide to the appropriate precautionary handling of the material by a properly trained person using this product. The above information has been compiled from various sources and has the possibility of discrepancy and being out-dated information. Individuals receiving the information must exercise their independent judgment and do further search in determining its appropriateness for a particular purpose. In no case shall our company be liable to loss or damages by the product user.
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