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Polysorbate 80 BP FCC Food Grade Manufacturers, SDS GHS MSDS Sheet

Polysorbate 80: CAS Number: 9005-65-6, EINECS EC Number: ----, Molecular Formula: C64H124O26, Molecular Weight: 1310, FEMA Number 2917, HS Code ---**

For MSDS Sheet Click
SDS MSDS Sheet of Polysorbate 80 Manufacturers

Polysorbate 80
Pure BP USP FCC Food Grade
Polysorbate 80

We ofer polysorbate 20, polysorbate 40, polysorbate 60, polysorbate 65 and polysorbate 80.

Polysorbate 80 is a nonionic surfactant and emulsifier often used in foods and cosmetics. This synthetic compound is a viscous, water-soluble yellow liquid.

Polysorbate 80
Polyoxyethylene 20 Sorbitan Mono-oleate
Ph Eur
Action and use: Non-ionic surfactants.

DEFINITION
Mixture of partial esters of fatty acids, mainly Oleic acid (0799), with sorbitol and its anhydrides ethoxylated with approximately 20 moles of ethylene oxide for each mole of sorbitol and sorbitol anhydrides.

CHARACTERS
Appearance: Oily, yellowish or brownish-yellow, clear or slightly opalescent liquid.
Solubility: Dispersible in water, in anhydrous ethanol, in ethyl acetate and in methanol, practically insoluble in fatty oils and in liquid paraffin.
Relative density: About 1.10.
Viscosity: About 400 mPa·s at 25 °C.

IDENTIFICATION
First identificationıA, D.
Second identificationıB, C, D, E.
A. Infrared absorption spectrophotometry.
B. Hydroxyl value (see Tests).
C. Saponification value (see Tests).
D. Composition of fatty acids.
E. Dissolve 0.1 g in 5 ml of methylene chloride R. Add 0.1 g of potassium thiocyanate R and 0.1 g of cobalt nitrate R. Stir with a glass rod. The solution becomes blue.

TESTS
Acid value: Maximum 2.0.
Hydroxyl value: 65 to 80.
Peroxide value: Maximum 10.0.
Saponification value: 45 to 55, determined on 4.0 g.
Composition of fatty acids: To pass the test.
Ethylene oxide and dioxan: Maximum 1 ppm of ethylene oxide and maximum 10 ppm of dioxan.
Heavy metals: Maximum 10 ppm.
Water: Maximum 3.0 per cent, determined on 1.00 g.
Total ash: Maximum 0.25 per cent, determined on 2.0 g.

Polysorbate 80 FCC Food Grade
Polyoxyethylene (20) Sorbitan Monooleate; Sorbitan Mono-
9-octadecenoate; Poly(oxy-1,2-ethanediyl) Derivative
INS: 433 CAS: [9005-65-6]

DESCRIPTION
Polysorbate 80 occurs as a yellow to orange colored, oily liquid. It is a mixture of oleate partial esters of sorbitol and sorbitol anhydrides condensed with approximately 20 moles of ethylene oxide (C2H4O) for each mole of sorbitol and its mono- and dianhydrides. It is very soluble in water, producing a nearly colorless solution, and it is soluble in alcohol, in fixed oils, in ethyl acetate, and in toluene. It is insoluble in mineral oil.
Function: Emulsifier; stabilizer.

REQUIREMENTS
Identification
A. Add 5 mL of 1 N sodium hydroxide to 5 mL of a 1:20 aqueous solution, boil for a few minutes, cool, and acidify with 2.7 N hydrochloric acid. The solution is strongly opalescent.
B. Add bromine dropwise, to a 1:20 aqueous solution. The bromine is decolorized.
C. A 60:40 (v/v) mixture of Polysorbate 80:water at 25C or below yields a gelatinous mass.

Assay for Oxyethylene Content: Not less than 65.0% and not more than 69.5% of oxyethylene groups (—C2H4O—), equivalent to between 96.5% and 103.5% of Polysorbate 80, calculated on the anhydrous basis.
Acid Value: Not more than 2.
1,4-Dioxane: Not more than 10 mg/kg.
Hydroxyl Value: Between 65 and 80.
Lead: Not more than 2 mg/kg.
Oleic Acid: Between 22 and 24 g per 100 g of sample.
Residue on Ignition: Not more than 0.25%.
Saponification Value: Between 45 and 55.
Water: Not more than 3.0%.

For Original Monographs of IP Indian Pharmacopoeia BP British Pharmacopoeia USP US Pharmacopoeia FCC Food Grade product, please check with the respective web-pages or books.

Manufacturers:

MUBY CHEMICALS
Ambernath Mumbai, Ankleshwar Gujarat, India
TEL: (OFFICE) 91-22-23770100, 23726950
Current Date Time in India GMT+5:30

e-mail: info@mubychem.com

USA & Canadian Customers may
e-mail: usa@mubychem.com
Call toll-free 1-844-682-9243 (1-844-MUBYCHEM)

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Last 14 August, 2017

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Calcium Acetate Calcium Chloride
Calcium Gluconate Calcium Hydroxide
Calcium Lactate Calcium Oxide
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Chromic Chloride Citric Acid
Calcium Citrate Copper Gluconate
Copper Sulfate, Cupric Sulphate Cupric Chloride
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Fumaric Acid Ferrous Sulphate
Ferric Sulfate Ferric Ammonium Citrate
Ferric Chloride  
Gentian Violet Mannitol
Magnesium Chloride Magnesium Gluconate
Magnesium Lactate Dihydrate Magnesium Sulfate
Magnesium Trisilicate Maleic Acid
Malic Acid BP USP Manganese Gluconate
Manganese Sulfate Manganese Chloride
Methylene Blue Potassium Bromide
Potassium Chloride Potassium Gluconate
Potassium Bitartrate, Cream of Tartar Potassium Hydroxide
Potassium Iodide Potassium Iodate
Potassium Sorbate Sodium Acetate
Sodium Bicarbonate Sodium Butyrate
Sodium Caprylate Sodium Fluoride
Sodium Gluconate Sodium Hydroxide Pellets
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Sodium Perborate Sodium Propionate
Sodium Thiosulfate Sodium Sulfate
Stannous Chloride Dihydrate Zinc Carbonate
Zinc Chloride Zinc Gluconate
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Polysorbate 80 SDS MSDS Sheet, Material Safety Data Sheet

1. PRODUCT DESCRIPTION

Product Name: Polysorbate 80
Synonyms: Polyoxyethylene 20 Sorbitan Mono-oleate
CAS Number: 9005-65-6
EINECS EC Number: 500-019-9
Molecular Weight: 2917
Molecular Formula: C64H124O26
Recommended usage: Industrial Manufacturing.
Suppliers: As per letterhead.

2. HAZARD IDENTIFICATION

GHS, Globally Harmonized System Classification in accordance with 29 CFR 1910
Classification according to Regulation (EC) No 1272/2008

Not a hazardous substance or mixture according to Regulation (EC) No. 1272/2008.
This substance is not classified as dangerous according to Directive 67/548/EEC.

Labeling according to GHS & Regulation (EC) No 1272/2008

GHS Label Elements
None

Signal Words: None

Hazards not otherwise classified (HNOC):
May causes mild skin irritation.
May causes mild eye irritation.

Precautionary statements:
P261: Avoid breathing dust/fume/gas/mist/vapors/spray.
P262: Do not get in eyes, on skin, or on clothing.
P281: Use personal protective equipment as required.
P302+P352 - IF ON SKIN: Wash with plenty of soap and water.
P303+P361+P353 - IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower.
P304 + P340 - IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P305 + P351 + P338 - IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P337+313: If eye irritation persists get medical advice/attention.

3. COMPOSITION/INFORMATION ON INGREDIENTS

Principal Components: Polysorbate 80
CAS Number: 9005-65-6
EINECS EC Number: 500-019-9

4. FIRST AID MEASURES

Always get medical attention after the first aid is over.

Emergency and First Aid Procedures:
Eyes - Flush with water for at least 15 minutes, raising and lowering eyelids occasionally. Get medical attention if irritation persists.
Skin - Thoroughly wash exposed area for at least 15 minutes. Remove contaminated clothing. Launder contaminated clothing before reuse. Get medical attention if irritation persists.
Ingestion - If Polysorbate 80 is swallowed, if conscious, give plenty of water. Immediately call a physician. Never give anything by mouth to an unconscious person.
Inhalation - Remove to fresh air. Give oxygen if breathing is difficult; give artificial respiration if breathing has stopped. Get medical attention.

5. FIREFIGHTING PROCEDURES

Extinguisher Media: Water spray. Carbon dioxide (CO 2). Dry chemical. alcohol-resistant foam.
Flammable Limits in Air % by Volume: N/A
Special Fire fighting Procedures: Firefighters should wear full protective equipment and NIOSH approved self-contained breathing apparatus.

6. SPILL OR LEAK PROCEDURES

Steps to be taken in Case Polysorbate 80 is Released or Spilled:
Ventilate area of leak or spill. Wear appropriate personal protective equipment.
Sweep up and containerize for reclamation or disposal. Vacuuming or wet sweeping may be used to avoid dust dispersal. Do not let product enter drains. Small amounts of residue may be flushed to sewer with plenty of water.

7. SPECIAL PRECAUTIONS

Keep Polysorbate 80 in a well closed container stored under cold to warm conditions in a ventilated area. Protect against physical damage. Containers of this material may be hazardous when empty since they retain product residues (dust, solids); observe all warnings and precautions listed for the product.

8. SPECIAL PROTECTION INFORMATION

Exposure Guidelines: This product does not contain any hazardous materials with occupational exposure limits established by the region specific regulatory bodies.
Respiratory Protection (Specify Type): None needed under normal conditions of use with adequate ventilation. NIOSH approved equipment should be worn if PELs are exceeded.
Ventilation Local Exhaust: Yes
Eye Protection: Splash proof chemical safety goggles should be worn at all times.
Other Protective Clothing or Equipment: Lab apron, eye wash, and safety shower.

9. PHYSICAL DATA

Molecular Weight: 2917
Molecular Formula: C64H124O26
Appearance and Odor: Dark yellow liquid material. Odorless.
Melting Point: NA.
Boiling Point: NA.
Density: 1.06 g/cm3

10. REACTIVITY DATA

Stability: Polysorbate 80 is stable
Conditions to Avoid: Heat.
Incompatibility (Materials to Avoid): Strong oxidizing and bases.
Hazardous Decomposition Products: Carbon monoxide, carbon dioxide
Hazardous Polymerization: Will not occur

11. TOXICITY DATA

LD50 Oral - Rat - > 63,840 mg/kg
Carcinogenicity: No product present at levels greater than or equal to 0.1% is identified as probable, possible or confirmed human carcinogen by IARC, NTP, ACGIH & OSHA.

12. ECOLOGICAL DATA

Toxicity: Avoid release into the environment.
Persistence and degradability: No data available

13. DISPOSAL INFORMATION

Waste Disposal Methods: Dispose Polysorbate 80 in accordance with all applicable Federal, State and Local regulations.

14. TRANSPORT INFORMATION

DOT & ADR/RID: Not regulated.
IMDG: Not regulated.
IATA: Not regulated.

15. REGULATORY INFORMATION

USA:
OSHA Hazards
: No known OSHA hazards
SARA 302 Components: SARA 302: No chemicals in this material are subject to the reporting requirements of SARA Title III, Section 302.
SARA 313 Components: This material does not contain any chemical components with known CAS numbers that exceed the threshold (De Minimis) reporting levels established by SARA Title III, Section 313.
SARA 311/312 Hazards: No SARA Hazards
California Prop. 65 Components: This product does not contain any chemicals known to State of California to cause cancer, birth defects, or any other reproductive harm.

DSCL (EEC): EINECS EC Number: 500-019-9.

Canada WHMIS: Not controlled under WHMIS (Canada)

Section 16 - Additional Information

DISCLAIMER: The information and recommendations set forth herein (hereinafter "Information") are presented in good faith and believed correct as of the date hereof. It is compiled from various sources and it is not necessarily all inclusive nor fully adequate in every circumstance. In addition, these suggestions should not be confused with nor followed in violation of applicable laws, regulations, rules or insurance requirements applicable. This MSDS sheet is intended only as a guide to the appropriate precautionary handling of the material by a properly trained person using this product. Individuals receiving the information must exercise their independent judgment in determining its appropriateness for a particular purpose.