L-Asparagine Monohydrate or (S)-(+)-2-Aminosuccinamic acid or (S)-2-Aminosuccinic acid 4-amide or L-Aspartic acid 4-amide USP BP Ph Eur Grade Manufacturers, with SDS GHS MSDS Sheet

Supplier, Manufacturer, Exporter of L-Asparagine Monohydrate or (S)-(+)-2-Aminosuccinamic acid or (S)-2-Aminosuccinic acid 4-amide or L-Aspartic acid 4-amide, Muby Chemicals of Mubychem Group, established in 1976, is the original manufacturers of Specialty Chemicals, Pharmaceutical Excipient, Fragrance Food & Flavor chemicals, Reagent Grade Chemicals, Shale Gas Fracturing Chemicals in India. Mubychem Group has several manufacturing facilities spread across Western India and world wide contacts and toll manufacturers. We are exporting globally to countries like USA, Canada, Europe, UAE, South Africa, Tanzania, Kenya, Egypt, Nigeria, Cameroon, Uganda, Turkey, Mexico, Brazil, Chile, Argentina, Dubai, Korea, Vietnam, Thailand, Malaysia, Indonesia, Australia, China, Germany, France, Italy, Portugal etc.

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L-Asparagine Monohydrate or (S)-(+)-2-Aminosuccinamic acid or (S)-2-Aminosuccinic acid 4-amide or L-Aspartic acid 4-amide CAS Number 5794-13-8 for monohydrate and 70-47-3 for anhydrous, EINECS EC Number: 200-735-9 or 611-593-6, Molecular Formula: C4H8N2O3-H2O or NH2COCH2CH(NH2)COOH-H2O, Molecular Weight: 150.13, HS Code 29224990 or 29241900

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SDS MSDS Sheet of L-Asparagine Monohydrate or (S)-(+)-2-Aminosuccinamic acid or (S)-2-Aminosuccinic acid 4-amide or L-Aspartic acid 4-amide Manufacturers

L-Asparagine Monohydrate
(S)-(+)-2-Aminosuccinamic acid or (S)-2-Aminosuccinic acid 4-amide or L-Aspartic acid 4-amide USP BP Ph Eur Grade Suppliers
L-Asparagine Monohydrate

General Properties and Specifications of L-Asparagine Monohydrate or (S)-(+)-2-Aminosuccinamic acid or (S)-2-Aminosuccinic acid 4-amide or L-Aspartic acid 4-amide:
Appearance: White crystalline compound.
Solubility of 10% solution in 2N HCl: Clear colourless.
Assay: 99% minimum.
pH: 4.0 to 5.5 for 20 g/l in water @ 20C.
Specific rotation [α]: +32° to +34° (C=5, 5N HCl)
Loss on drying: 10.0 - 12.5%
Sulphated Ash: 0.1% maximum.
Chloride (CI): 0.02% maximum.
Sulphate (SO4): 0.03% maximum.
Iron (Fe): 0.001% maximum.
Heavy Metals (Pb): 0.001% maximum.
Ammonium (NH4): 0.02% maximum.
Homogeneity by TLC: Passes test.
Suitability for Tissue Culture: Passes test.
Melting point: 233C to 235C.
Storage: Room Temperature.


Asparagine USP NF Grade Specifications:
C4H8N2O3-H2O --- 150.13
C4H8N2O3 --- 132.12
l-Asparagine;
l-α-Aminosuccinamic acid, monohydrate CAS 5794-13-8
Anhydrous CAS 70-47-3
UNII: 2PD79VF521

DEFINITION
Asparagine is anhydrous or contains one molecule of water of hydration. It contains NLT 98.0% and NMT 101.5% of C4H8N2O3 as l-asparagine, calculated on the dried basis.

IDENTIFICATION
A. Infrared Absorption.
Residue on Ignition: NMT 0.1%
Lead: NMT 5 ppm.
Chromatographic Purity: To pass the test.
Optical Rotation, Specific Rotation: 10 mg/mL, in 6 N hydrochloric acid +33.0° to +36.5°, measured at 20°
Microbial Enumeration Tests and Tests for Specified Microorganisms: The total aerobic microbial count does not exceed 1000 cfu/g, and the total combined molds and yeasts count does not exceed 100 cfu/g.
Loss on Drying: Dry a sample at 130C for 3 h: the anhydrous form loses NMT 1.0% of its weight, and the monohydrate loses between 11.5% and 12.5% of its weight.


Asparagine Monohydrate BP Ph Eur Grade Specifications:
C4H8N2O3-H2O --- 150.1 CAS 5794-13-8
Action and use: Amino acid.

DEFINITION
(2S)-2,4-Diamino-4-oxobutanoic acid monohydrate.
Content: 99.0 per cent to 101.0 per cent (dried substance).

CHARACTERS
Appearance: White or almost white, crystalline powder or colourless crystals.
Solubility: Slightly soluble in water, practically insoluble in ethanol (96 per cent) and in methylene chloride.

IDENTIFICATION
First identification: A, B
Second identification: A, C
A. Specific optical rotation.
B. Infrared absorption spectrophotometry.
C. Examine the chromatograms obtained in the test for ninhydrin-positive substances.

TESTS
Solution S: Dissolve with heating 2.0 g in carbon dioxide-free water and dilute to 100 mL with the same solvent.
Appearance of solution: Solution S is clear and colourless.
pH: 4.0 to 6.0 for solution S.
Specific optical rotation: + 33.7 to + 36.0 (dried substance).
Ninhydrin-positive substances: To pass the test.
Chlorides: Maximum 200 ppm.
Sulfates: Maximum 200 ppm.
Ammonium: Maximum 0.1 per cent, determined on 10 mg.
Iron: Maximum 10 ppm.
Loss on drying: 10.5 per cent to 12.5 per cent, determined on 1.000 g by drying in an oven at 130C for 3 h.
Sulfated ash: Maximum 0.1 per cent, determined on 1.0 g.

For Original Monographs of IP Indian Pharmacopoeia BP British Pharmacopoeia USP US Pharmacopoeia FCC Food Grade product, please check with the respective web-pages or books.

We also manufacture and supply as under:

Aspartame

Aspartic Acid

L-Asparagine Monohydrate or (S)-(+)-2-Aminosuccinamic acid

Calcium Aspartate

Carbamide Peroxide

Iron Aspartate

Magnesium Aspartate

N-Bromosuccinimide

N-Iodosuccinimide

Succinic Acid

1,10-Phenanthroline Monohydrate.

Manufacturers:

MUBY CHEMICALS
Ambernath Mumbai, Ankleshwar Gujarat, India
TEL: (OFFICE) +912223770100, +912223726950
Current Date Time in India GMT+5:30

e-mail: info@mubychem.com

USA, Canada, Mexico and other American
neighbouring buyers may
e-mail: us@mubychem.com
Call toll-free 1-877-682-9243 (1-877-MUBYCHEM)

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Last 30 October, 2023

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L-Asparagine Monohydrate or (S)-(+)-2-Aminosuccinamic acid or (S)-2-Aminosuccinic acid 4-amide or L-Aspartic acid 4-amide SDS, Safety Data Sheet
MSDS Sheet, Material Safety Data Sheet
21-Mar-22

1. PRODUCT DESCRIPTION

Product Name & Other Names: L-Asparagine Monohydrate or (S)-(+)-2-Aminosuccinamic acid or (S)-2-Aminosuccinic acid 4-amide or L-Aspartic acid 4-amide.
CAS Number: 5794-13-8 for monohydrate and 70-47-3 for anhydrous
EINECS EC Number: 200-735-9 or 611-593-6
Molecular Formula: C4H8N2O3-H2O or NH2COCH2CH(NH2)COOH-H2O
Molecular Weight: 150.13
Relevant uses and uses advised against (if any): Industrial Manufacturing.
Suppliers: As per letterhead.

2. HAZARD IDENTIFICATION

GHS, Globally Harmonized System Classification in accordance with 29 CFR 1910
Hazard Class and Category Code(s), Regulation (EC) No 1272/2008 (CLP)

Not a hazardous substance or mixture according to Regulation (EC) No. 1272/2008.
This substance is not classified as dangerous according to Directive 67/548/EEC.

Labeling as per GHS & Regulation EC 1272/2008 (CLP) & GHS

GHS Label Elements
None

Signal Words: None

Hazards not otherwise classified (HNOC):
May causes mild skin irritation.
May causes mild eye irritation.

Precautionary statements:
P261: Avoid breathing dust/fume/gas/mist/vapors/spray.
P262: Do not get in eyes, on skin, or on clothing.
P281: Use personal protective equipment as required.
P302+P352 - IF ON SKIN: Wash with plenty of soap and water.
P304 + P340 - IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P305 + P351 + P338 - IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P337+313: If eye irritation persists get medical advice/attention.

3. COMPOSITION/INFORMATION ON INGREDIENTS

Product Name & Other Names: L-Asparagine Monohydrate or (S)-(+)-2-Aminosuccinamic acid or (S)-2-Aminosuccinic acid 4-amide or L-Aspartic acid 4-amide.
CAS Number: 5794-13-8 for monohydrate and 70-47-3 for anhydrous
EINECS EC Number: 200-735-9 or 611-593-6

4. FIRST AID MEASURES

Always get medical attention after the first aid is over.

Eyes - Flush with water for at least 15 minutes, raising and lowering eyelids occasionally. Get medical attention if irritation persists.
Skin - Thoroughly wash exposed area for at least 15 minutes. Remove contaminated clothing. Launder contaminated clothing before reuse. Get medical attention if irritation persists.
Ingestion - If swallowed, if conscious, give plenty of water. Immediately call a physician. Never give anything by mouth to an unconscious person.
Inhalation - Remove to fresh air. Give oxygen if breathing is difficult; give artificial respiration if breathing has stopped. Get medical attention.

5. FIREFIGHTING PROCEDURES

Extinguisher Media: Use media suitable to extinguish surrounding fire. Water. Foam. Dry chemical or CO2. Oxides of Carbon and Nitrogen may arise on decomposition.
Flammable Limits in Air % by Volume: N/A
Special Firefighting Procedures: Firefighters should wear full protective equipment and NIOSH approved self-contained breathing apparatus. Use water spray to cool unopened containers.
Special Information: In the event of a fire, wear full protective clothing and NIOSH-approved self-contained breathing apparatus with full face piece operated in the pressure demand or other positive pressure mode. At high temperatures under fire conditions, it may produce toxic or irritating fumes. Fire-extinguishing work is done from the windward and a suitable fire-extinguishing method according to the surrounding situation is used. Uninvolved persons should evacuate to a safe place.

6. SPILL OR LEAK PROCEDURES

Personal precautions, protective equipment, and emergency procedures: Avoid breathing dust/fumes/gas/mist/vapors/spray. Use individual protective equipment (waterproof boots, suitable protective clothing, safety glasses, etc.). Restrict unprotected personnel from the area. Prevent any contact with hot surfaces. Do not approach facing the wind. Do not touch the spilled material.
Environmental precautions: Do not let the product enter drains, soil, or water sources.
Methods and materials used for containment cleanup procedures and Storage: Do not inhale dust, vapors, mist, or gas. Avoid dust formation. Contain spilled material. Cover with an inert, non-combustible absorbent material, (e.g., sand, earth, diatomaceous earth, vermiculite). Use a shovel to put the material into a convenient waste disposal container. Finish cleaning by spreading water on the contaminated surface and allow to evacuate as per law.

7. SPECIAL PRECAUTIONS

Precautions for safe handling: Apply according to good manufacturing and industrial hygiene practices. Ensure proper ventilation. In case of insufficient ventilation, wear suitable respiratory equipment. Wash thoroughly after handling. Do not drink, eat, or smoke while handling. Avoid contact with skin, eyes, and clothing. Minimize dust generation. Avoid breathing dust/fumes/gas/mist/vapors/spray. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation. Use individual protective equipment (waterproof boots, suitable protective clothing, safety glasses, etc.). Prevent any contact with hot surfaces.
Conditions for safe storage, including any incompatibilities: Store in cool, dry, and ventilated area away from heat sources and protected from sunlight in tightly closed original container. Keep air contact to a minimum. Store protected from heat, sparks and ignition sources and incompatible materials. Avoid contact with skin and eyes. Avoid inhalation of dust/mist/vapor. Do not store with incompatible materials like strong oxidizing agents. Storage: Room Temperature.

8. SPECIAL PROTECTION INFORMATION

Exposure Guidelines: This product, as supplied, does not contain any hazardous materials with occupational exposure limits established by the region-specific regulatory bodies.
Respiratory Protection (Specify Type): None needed under normal conditions of use with adequate ventilation. NIOSH approved equipment should be worn if PELs are exceeded.
Ventilation System: A system of local and/or general exhaust is recommended to keep employee exposures as low as possible. Local exhaust ventilation is generally preferred because it can control the emissions of the contaminant at its source, preventing dispersion of it into the general work area.
Personal Respirators (NIOSH Approved): For conditions of use where exposure to dust or mist is apparent and engineering controls are not feasible, a particulate respirator may be worn. For emergencies or instances where the exposure levels are not known, use a full-face positive-pressure, air-supplied respirator.
Skin Protection: Wear protective gloves and clean body-covering clothing.
Eye Protection: Use chemical safety goggles and/or full-face shield where dusting or splashing of solutions is possible. Maintain eye wash fountain and quick-drench facilities in work area.
Other Control Measures: Maintain good housekeeping in work area. Handle in accordance with good industrial hygiene and safety practice. Wash hands after handling. Store in a freezer.

9. PHYSICAL DATA

Appearance and Odor: White crystalline compound.
Odor: Not available.
Odor threshold: Not available.
pH: 4.0 to 5.5 for 20 g/l in water @ 20C.
Relative density: Not available.
Melting point/freezing point: 233C to 235C.
Initial boiling point and boiling range: Not available.
Flash point: Not available.
Auto-ignition temperature: Not available.
Decomposition temperature: Not available.
Upper/lower flammability or explosive limits: Not available.
Vapor pressure: Not available.
Vapor density: Not available.
Evaporation rate: Not available.
Flammability (solid, gas): Not available.
Partition coefficient: n-octanol/water: Not available.
Solubility in Water: Soluble in water.
Viscosity: Not available.
Molecular Formula: C4H8N2O3-H2O or NH2COCH2CH(NH2)COOH-H2O
Molecular Weight: 150.13

10. REACTIVITY DATA

Stability: Stable under ordinary conditions.
Conditions to Avoid: Heat, humidity, sunlight, strong oxidizing agents.
Incompatibility (Materials to Avoid): Strong oxidizing agents.
Hazardous Decomposition Products: Carbon and Nitrogen oxides.
Hazardous Polymerization: Will not occur.

11. TOXICITY DATA

Toxicity to Animals: Not available.
Carcinogenicity: No component of this product present at levels greater than or equal to 0.1% is identified as possible or confirmed human carcinogen by IARC, ACGIH, OSHA and NTP.
Teratogenic Effects: Not available.
Mutagenic Effects: Not available.
Developmental Toxicity: Not available.
Reproductive Effects: No information available.

12. ECOLOGICAL DATA

Toxicity to fish: No information available.
Persistence and Degradability: No information available.
Mobility: No information available.
Bioaccumulation/ Accumulation: No information available.
Results of PBT and vPvB assessment: No data available for assessment.

13. DISPOSAL INFORMATION

Waste Disposal Methods: Dispose in accordance with all applicable Federal, State and Local regulations.

14. TRANSPORT INFORMATION

DOT USA, TDG Canada & ADR/RID Europe: Not regulated.
IMO/IMDG: Not regulated.
IATA/ICAO: Not regulated.

15. REGULATORY INFORMATION

USA:
SARA 311/312 Hazards
: No SARA Hazards
California Prop. 65 Components: This product does not contain any chemicals known to the State of California to cause cancer, birth defects, or any other reproductive harm.

16. ADDITIONAL INFORMATION

Disclaimer:
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Our company provides this MSDS sheet in good faith but makes no representation as to its comprehensiveness or accuracy. This SDS sheet is intended only as a guide to the appropriate precautionary handling of the material by a properly trained person using this product. The above information has been compiled from various sources and has the possibility of discrepancy and being out-dated information. Individuals receiving the information must exercise their independent judgment and do further search in determining its appropriateness for a particular purpose. In no case shall our company be liable to loss or damages by the product user.
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