PVAP or Polyvinyl Acetate Phthalate USP NF Grade Manufacturers, with SDS GHS MSDS Sheet

Supplier, Manufacturer, Exporter of PVAP or Polyvinyl Acetate Phthalate Muby Chemicals of Mubychem Group, established in 1976, is the original manufacturers of Specialty Chemicals, Pharmaceutical Excipient, Fragrance Food & Flavor chemicals, Reagent Grade Chemicals, Shale Gas Fracturing Chemicals in India. Mubychem Group has several manufacturing facilities spread across Western India and world wide contacts and toll manufacturers. We are exporting globally to countries like USA, Canada, Europe, UAE, South Africa, Tanzania, Kenya, Egypt, Nigeria, Cameroon, Uganda, Turkey, Mexico, Brazil, Chile, Argentina, Dubai, Korea, Vietnam, Thailand, Malaysia, Indonesia, Australia, China, Germany, France, Italy, Portugal etc.

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PVAP or Polyvinyl Acetate Phthalate CAS Number 34481-48-6 and 53237-50-6 is also used, Molecular Formula: C8H6O4-C4H6O2 or C12H12O6, Molecular Weight: 252.22, HS Code 39051290

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SDS MSDS Sheet of PVAP or Polyvinyl Acetate Phthalate Manufacturers

Polyvinyl Acetate Phthalate
PVAP Pure Suppliers
PVAP or Polyvinyl Acetate Phthalate

Polyvinyl acetate phthalate or PVAP is a commonly used polymer phthalate in the formulation of pharmaceuticals, such as the enteric coating of tablets or capsules. It is a vinyl acetate polymer that is partially hydrolyzed and then esterified with phthalic acid. Its main use in pharmaceutics is with enteric formulations and controlled release formulations.

Polyvinyl Acetate Phthalate USP NF Grade Specifications:

DEFINITION
Polyvinyl Acetate Phthalate is a reaction product of phthalic anhydride and a partially hydrolyzed polyvinyl acetate. It contains NLT55.0% and NMT 62.0% of phthalyl (o-carboxybenzoyl, C8H5O3) groups, calculated on the anhydrous, acid-free basis.

IDENTIFICATION
A. The Sample solution in the Assay exhibits a maximum at 277 ± 3 nm.
B.
Sample:10 mg
Analysis: Place the Sample in a small test tube, add 10 mg of resorcinol, and mix. Add 0.5 mL of sulfuric acid, and heat in a liquid bathat 160° for 3 min. Cool, and pour the solution into a mixture of 25 mL of 1 N sodium hydroxide and 200 mL of water.
Acceptance criteria: The solution shows a vivid green fluorescence.
C.
Sample solution: 100 mg/mL of Polyvinyl Acetate Phthalate in methanol
Analysis: Pour 1 mL of the Sample solution onto a clear glass plate.
Acceptance criteria: A film is deposited as the methanol evaporates.

ASSAY
Phthalyl content:
Acceptance criteria: 55.0% to 62.0% of phthalyl (o-carboxybenzoyl, C8H5O3) groups on the anhydrous, acid-free basis

Residue on ignition: NMT 1.0%
Free phthalic acid:
Acceptance criteria: NMT 0.6% on the anhydrous basis
Free acid other than phthalic:
Acceptance criteria: NMT 0.6% on the anhydrous basis
Viscosity - capillary methods:
Acceptance criteria: The apparent viscosity is 7 to 11 mPa · s (centipoises).
Water determination: nmt 5.0%
Packaging and storage: Preserve in tight containers.

For Original Monographs of IP Indian Pharmacopoeia BP British Pharmacopoeia USP US Pharmacopoeia FCC Food Grade product, please check with the respective web-pages or books.

We also manufacture and supply as under:

Cellulose Acetate Phthalate

Diethyl Phthalate or DEP

Dimethyl Terephthalate

Dioctyl Phthalate or Di(2-ethylhexyl) Phthalate

Polyvinyl Acetate

Polyvinyl Alcohol

Polyvinyl Acetate Phthalate

PVDC, Polyvinylidene Chloride

Povidone; Polyvinylpyrrolidone.

Manufacturers:

MUBY CHEMICALS
Ambernath Mumbai, Ankleshwar Gujarat, India
TEL: (OFFICE) +912223770100, +912223726950
Current Date Time in India GMT+5:30

e-mail: info@mubychem.com

USA, Canada, Mexico and other American
neighbouring buyers may
e-mail: us@mubychem.com
Call toll-free 1-877-682-9243 (1-877-MUBYCHEM)

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Copyright and Usual Disclaimer is Applicable.
Last 4 October, 2023

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PVAP or Polyvinyl Acetate Phthalate SDS GHS, Safety Data Sheet
MSDS Sheet, Material Safety Data Sheet
 10-June-23

Section 1: Chemical Product and Company Identification

Product Name & Other Names: PVAP or Polyvinyl Acetate Phthalate.
CAS Number
: 34481-48-6 and 53237-50-6 is also used.
EINECS EC Code: -
Molecular Weight: 252.22
Chemical Formula: C8H6O4-C4H6O2 or C12H12O6
Relevant uses and uses advised against (if any): Industrial Manufacturing.
Suppliers: As per letterhead.

Section 2: Hazards Identification

GHS, Globally Harmonized System Classification in accordance with 29 CFR 1910
Hazard Class and Category Code(s), Regulation (EC) No 1272/2008 (CLP)

Not a hazardous substance or mixture according to Regulation (EC) No. 1272/2008.
This substance is not classified as dangerous according to Directive 67/548/EEC

Labeling Regulation as per GHS & EC 1272/2008 (CLP) & GHS

GHS Label Elements
NONE

Signal Word: None

Hazards not otherwise classified (HNOC):
May causes mild skin irritation.
May causes mild eye irritation.

Precautionary statements:
P261: Avoid breathing dust/fume/gas/mist/vapors/spray.
P262: Do not get in eyes, on skin, or on clothing.
P281: Use personal protective equipment as required.
P302+P352 - IF ON SKIN: Wash with plenty of soap and water.
P303+P361+P353 - IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower.
P304 + P340 - IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P305 + P351 + P338 - IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P337+313: If eye irritation persists get medical advice/attention.

Section 3: Composition and Information on Ingredients

Product Name & Other Names: PVAP or Polyvinyl Acetate Phthalate.
CAS Number
: 34481-48-6 and 53237-50-6 is also used.

Section 4: First Aid Measures

Always seek medical advice after the first aid treatment.

Skin: Rinse with water. Soap may be used. Seek Medical Aid.
Eyes: Wash eyes with plenty of water for at least 15 minutes, lifting lids occasionally. Seek Medical Aid.
Inhalation: Remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen.
Ingestion: If swallowed, induce vomiting immediately after giving two glasses of water. Never give anything by mouth to an unconscious person.
Treatment: Treat symptomatically.

Section 5: Fire and Explosion Data

Products of Combustion: Oxides of Carbon.
Fire Fighting Media and Instructions: Use water spray, alcohol-resistant foam, dry chemical, or carbon dioxide. Wear self-contained breathing apparatus for firefighting if necessary.
General: Powdered material may form explosive dust-air mixtures.
Special Information: In the event of a fire, wear full protective clothing and NIOSH-approved self-contained breathing apparatus with full face piece operated in the pressure demand or other positive pressure mode. At high temperatures under fire conditions, it may produce toxic or irritating fumes.

Section 6: Accidental Release Measures

Personal precautions, protective equipment, and emergency procedures: Avoid breathing dust/fumes/gas/mist/vapors/spray. Use individual protective equipment (waterproof boots, suitable protective clothing, safety glasses, etc.). Restrict unprotected personnel from the area. Prevent any contact with hot surfaces. Do not approach facing the wind. Do not touch the spilled material.
Environmental precautions: Do not let the product enter drains, soil, or water sources.
Methods and materials used for containment cleanup procedures and Storage:
Small Spill: Use appropriate tools to put the spilled solid in a convenient waste disposal container. Finish cleaning by spreading water on the contaminated surface and dispose of according to legal requirements.
Large Spill: Contain spilled material. Do not inhale dust, vapors, mist, or gas. Avoid dust formation. Use a shovel to put the material into a convenient waste disposal container. Finish cleaning by spreading water on the contaminated surface and allow to evacuate as per law.

Section 7: Handling and Storage

Precautions for safe handling: Apply according to good manufacturing and industrial hygiene practices. Ensure proper ventilation. Wash thoroughly after handling. Do not drink, eat, or smoke while handling. Avoid contact with skin, eyes, and clothing. Minimize dust generation. Avoid breathing dust/fumes/gas/mist/vapors/spray. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation. Use individual protective equipment (waterproof boots, suitable protective clothing, safety glasses, etc.). Prevent any contact with hot surfaces.
Conditions for safe storage, including any incompatibilities: Store in cool, dry, and ventilated area away from heat sources and protected from sunlight in tightly closed original container. Keep air contact to a minimum. Do not leave the material container open. Store protected from heat, sparks and ignition sources and incompatible materials. Avoid contact with skin and eyes. Avoid inhalation of dust/mist/vapor. Do not store with incompatible materials like oxidizing agents. Polyvinyl acetate phthalate should be stored in airtight containers.

Section 8: Exposure Controls/Personal Protection

Exposure Guidelines: This product does not contain any hazardous materials with occupational exposure limits established by the region-specific regulatory bodies.
Engineering Controls: Use process enclosures, local exhaust ventilation, or other engineering controls to keep airborne levels below recommended exposure limits. If user operations generate dust, fume, or mist, use ventilation to keep exposure to airborne contaminants below the exposure limit.
Ventilation System: A system of local and/or general exhaust is recommended to keep employee exposures as low as possible. Local exhaust ventilation is generally preferred because it can control the emissions of the contaminant at its source, preventing dispersion of it into the general work area.
Personal Respirators (NIOSH Approved): For conditions of use where exposure to dust or mist is apparent and engineering controls are not feasible, a particulate respirator may be worn. For emergencies or instances where the exposure levels are not known, use a full-face positive-pressure, air-supplied respirator.
Skin Protection: Wear protective gloves and clean body-covering clothing.
Eye Protection: Use chemical safety goggles and/or full-face shield where dusting or splashing of solutions is possible. Maintain eye wash fountain and quick-drench facilities in work area.
Other Control Measures: Maintain good housekeeping in work area. Dust deposits on floors and other surfaces may pick up moisture and cause the surfaces to become slippery and present safety hazards. Handle in accordance with good industrial hygiene and safety practice. Wash hands after handling.

Section 9: Physical and Chemical Properties

Physical state and appearance: Solid off-white to white crystals powder or granules.
Odor: Not available.
Odor threshold: Not available.
pH: Not available.
Relative density: Not available.
Melting point/freezing point: Not available.
Initial boiling point and boiling range: Not available.
Flash point: Not available.
Auto-ignition temperature: Not available.
Decomposition temperature: Not available.
Upper/lower flammability or explosive limits: Not available.
Vapor pressure: Not available.
Vapor density: Not available.
Evaporation rate: Not available.
Flammability (solid, gas): Not available.
Partition coefficient: n-octanol/water: Not available.
Solubility: Not available.
Viscosity: Not available.

Section 10: Stability and Reactivity Data

Stability: It is stable in room temperature in closed containers under normal storage & handling.
Conditions of instability: Incompatible materials, Strong oxidizers.
Incompatibility with various substances: Avoid high temperatures, sparks, open flames, and moisture. Avoid contact with strong oxidizing agents. Avoid dust formation.
Polymerization: Will not occur.

Section 11: Toxicological Information

LD50 Oral - Rat: No data available.
Carcinogenic Effects: Not a reported carcinogen by IARC, NTP, ACGIH, OSHA.
Reproductive toxicity: No data available.
Teratogenicity: No data available.
Developmental Effects: No data available.

Section 12: Ecological Information

Toxicity to fish: No data available.
Persistence and degradability: Not available.
Mobility in soil: Not available.
Results of PBT and vPvB assessment: Not available.

Section 13: Disposal Considerations

Waste Disposal: Waste must be disposed of in accordance with federal, state, and local environmental control regulations.

Section 14: Transport Information

DOT (USA) & ADR/RID Europe: Not dangerous goods.
IMDG: Not dangerous goods.
IATA: Not dangerous goods.

Section 15: Other Regulatory Information

USA Regulations:
SARA 202: Not applicable
SARA 313: Not applicable
SARA 311/312 Hazard Categories: Not applicable
California Prop 65:California No Significant Risk Level: None of the chemicals in this product are listed.

Section 16 - Additional Information

Disclaimer:
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Our company provides this MSDS sheet in good faith but makes no representation as to its comprehensiveness or accuracy. This SDS sheet is intended only as a guide to the appropriate precautionary handling of the material by a properly trained person using this product. The above information has been compiled from various sources and has the possibility of discrepancy and being out-dated information. Individuals receiving the information must exercise their independent judgment and do further search in determining its appropriateness for a particular purpose. In no case shall our company be liable to loss or damages by the product user.
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