Sodium Calcium Edetate or Calcium Disodium EDTA Pure and BP Ph Eur USP NF, FCC Food Grade Manufacturers, with SDS GHS MSDS Sheet |
Supplier, Manufacturer, Exporter of Sodium Calcium Edetate or Calcium Disodium EDTA, Muby Chemicals of Mubychem Group, established in 1976, is the original manufacturers of Specialty Chemicals, Pharmaceutical Excipient, Fragrance Food & Flavor chemicals, Reagent Grade Chemicals, Shale Gas Fracturing Chemicals in India. Mubychem Group has several manufacturing facilities spread across Western India and world wide contacts and toll manufacturers. We are exporting globally to countries like USA, Canada, Europe, UAE, South Africa, Tanzania, Kenya, Egypt, Nigeria, Cameroon, Uganda, Turkey, Mexico, Brazil, Chile, Peru, Argentina, Dubai, Korea, Vietnam, Thailand, Malaysia, Indonesia, Australia, China, Germany, France, Italy, Portugal, Bangladesh, etc. The products are offered as per required specifications and in correct shape and size in mm or meshs or microns as specified by the buyer. The participating units have one or more accreditations like FDA - cGMP and GLP approval, ISO-9001 Certified, "REACH" Registered, ISO-14001, ISO/IEC 17025, ISO-22000, FSSC 22000, ISO 45001, Kosher Certified, Halal Certified, HACCP, FSSAI. We offer Commercial Pure & IP BP EP Ph Eur USP NF JP FCC Food Grade Analytical Reagent Grades of Chemicals |
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Sodium Calcium Edetate or Calcium Disodium Ethylene Diamine Tetraacetate or Calcium Disodium EDTA: 62-33-9 Anhydrous, 6381-92-6 Dihydrate and CAS 23411-34-9, EINECS EC Number: 200-529-9, Molecular Formula: C10H12O8CaN2Na2-2H2O, Molecular Weight: 374.27, HS Code 29173990
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Specifications, Safety Data Sheet, Manufacturing process details, Wholesale retail prices, Uses etc available on these pages for Sodium Calcium Edetate or Calcium Disodium Ethylene Diamine Tetraacetate or Calcium Disodium EDTA.
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SDS MSDS Sheet of Sodium Calcium Edetate or Calcium Disodium EDTA Manufacturers
Spanish Fabricantes de EDTA disódico de calcio
Portuguese EDTA disssódico de cálcio fabricantes
Calcium Disodium EDTA
Sodium Calcium Edetate or Calcium Disodium Ethylene Diamine Tetraacetate Pure BP Ph Eur USP NF, FCC Food Grade Suppliers
Synonyms: EDTA calcium disodium, Ethylenediaminetetraacetic acid calcium disodium salt, Edetate calcium disodium, Ethylenediaminetetraacetic Acid Disodium Calcium Salt, Calcium disodium ethylenediaminetetraacetate, Calcium disodium EDTA, Calcium disodium edetate
Sodium calcium edetate or Sodium calcium EDTA or Sodium Calcium Edetate or , also known as edetate calcium disodium among other names, is used as a medication to treat lead poisoning. It is a chelating agent, meaning that it binds to metals. When the metals are bound (or sequestered), they are prevented from taking part in chemical reactions that would lead to colour or flavor deterioration. Calcium disodium EDTA is a common popular food additive and flavoring agent and sequestrant, an ingredient in cosmetic and industrial products. It’s used in food to preserve flavor, color and texture. Calcium disodium EDTA is an odorless crystalline powder with a slightly salty flavor.
The USA FDA has approved calcium disodium EDTA as a safe food additive in small quantities. The E number of Calcium disodium EDTA is 385.
It is used in Mayonnaise Salad dressings, Sauces and Spreads, Pickled Vegetables, Canned crabs, Carbonated soft drinks & Alcoholic beverages. It is also used in Beauty and Cosmetic products, Paper and Textile.
General Specifications of Calcium Disodium EDTA
Synonym: Calcium Disodium Ethylene Diamine Tetraacetate.
CAS Number.: 62-33-9 Anhydrous and 6381-92-6 Dihydrate.
HSN No.: 29173990.
Appearance: White Crystalline Powder.
Solubility: Soluble In Water, Clear Solution.
Assay: 99.0% Minimum.
pH: 6.0 - 8.5.
Heavy Metals: 0.002% Maximum.
Edetate Calcium Disodium USP NF Grade Specifications
C10H12CaN2Na2O8.xH2O (anhydrous) --- 374.27
Calciate(2-), [[N,N′-1,2-ethanediylbis[N-(carboxymethyl)glycinato]](4-)-N,N′,O,O′,ON,ON′]-, disodium, hydrate, (OC-6-21)-. Disodium[(ethylenedinitrilo)tetraacetato]calciate(2-)hydrate [CAS 23411-34-9]. Anhydrous CAS [62-33-9].
Edetate Calcium Disodium is a mixture of the dihydrate and trihydrate of calcium disodium ethylenediaminetetraacetate (predominantly the dihydrate). It contains not less than 97.0 percent and not more than 102.0 percent of C10H12CaN2Na2O8, calculated on the anhydrous basis.
Packaging and storage: Preserve in tight containers.
A: Infrared Absorption.
B: A solution (1 in 20) responds to the oxalate test for Calcium and to the flame test for Sodium.
C: To 5 mL of water add 2 drops of ammonium thiocyanate and 2 drops of ferric chloride. To the deep red solution add about 50 mg of Edetate Calcium Disodium, and mix: the deep red color disappears.
pH: between 6.5 and 8.0, in a solution (1 in 5).
Water: not more than 13.0%.
Heavy metals: 0.002%.
Limit of nitrilotriacetic acid: To pass the test (0.1%).
Magnesium-chelating substances: Weigh accurately 1.0 g, transfer to a small beaker, and dissolve in 5 mL of water. Add 5 mL of ammonia-ammonium chloride buffer. Then to the buffered solution add 5 drops of eriochrome black, and titrate with 0.10 M magnesium acetate to the appearance of a deep wine-red color: not more than 2.0 mL is required.
Assay: Weigh accurately about 1.2 g of Edetate Calcium Disodium, transfer to a 250-mL beaker, and dissolve in 75 mL of water. Add 25 mL of 1 N acetic acid and 1 mL of diphenylcarbazone, and titrate slowly with 0.1 M mercuric nitrate to the appearance of the first purplish color. Perform a blank determination, and make any necessary correction. Each mL of 0.1 M mercuric nitrate is equivalent to 37.43 mg of C10H12CaN2Na2O8.
Sodium Calcium Edetate BP Ph Eur Grade Specifications:
C10H12CaN2Na2O8,xH2O --- 374.3 CAS 62-33-9
(anhydrous substance)
Action and use: Chelating agent.
DEFINITION
Disodium [(ethylenedinitrilo)tetraacetato]calciate(2-).
Content: 98.0 per cent to 102.0 per cent (anhydrous substance).
It contains a variable quantity of water of crystallisation.
CHARACTERS
Appearance: White or almost white, hygroscopic powder.
Solubility: Freely soluble in water, practically insoluble in ethanol (96 per cent).
IDENTIFICATION
First identification: A, C, D.
Second identification: B, C, D
A. Infrared absorption spectrophotometry.
B. Dissolve 2 g in 10& mL of water, add 6 mL of lead nitrate solution, shake and add 3 mL of potassium iodide solution. No yellow precipitate is formed. Make alkaline to red litmus paper by the addition of dilute ammonia and add 3 mL of ammonium oxalate solution. A white precipitate is formed.
C. Ignite. The residue gives a reaction of calcium.
D. Dissolve 0.5 g in 10 mL of water and add 10 mL of potassium pyroantimonate solution. A white, crystalline precipitate is formed. The formation of the precipitate is accelerated by rubbing the wall of the tube with a glass rod.
Solution S: Dissolve 5.0 g in water and dilute to 100 mL with the same solvent.
Appearance of solution: Solution S is clear and colourless
pH: 6.5 to 8.0.
Dissolve 5.0 g in carbon dioxide-free water and dilute to 25 mL with the same solvent.
Impurity A (nitrilotriacetic acid): To pass the test by liquid chromatograph.
Disodium edetate: Maximum 1.0 per cent.
Chlorides: Maximum 0.1 per cent.
Iron: Maximum 80 ppm.
Water: 5.0 per cent to 13.0 per cent, determined on 0.200 g.
Calcium Disodium EDTA FCC Food Grade Specifications
Calcium Disodium Ethylenediaminetetraacetate; Calcium
Disodium (Ethylenedinitrilo)tetraacetate; Calcium Disodium Edetate.
C10H12CaN2Na2O8-2H2O --- Formula weight 410.30
INS: 385 --- CAS 23411-34-9
DESCRIPTION
Calcium Disodium EDTA occurs as white, crystalline granules or as a white to off white powder. It is slightly hygroscopic and is stable in air. It is freely soluble in water.
Function: Preservative; sequestrant.
Identification:
A. A 1:20 aqueous solution responds to the oxalate test for Calcium and to the flame test for Sodium.
B. The infrared absorption spectrum of a mineral oil dispersion of sample exhibits maxima only at the same wavelengths as those of a similar preparation of USP Edetate Calcium Disodium Reference Standard.
C. Add 2 drops of ammonium thiocyanate and 2 drops of ferric chloride to 5 mL of water contained in a test tube. Add about 50 mg of sample to the deep red solution so obtained, and mix. The deep red color disappears.
Assay: Not less than 97.0% and not more than 102.0% of C10H12CaN2Na2O8, calculated on the anhydrous basis.
Lead: Not more than 4 mg/kg.
Magnesium-Chelating Substances: Passes test.
Nitrilotriacetic Acid: Not more than 0.1%.
pH of a 1:100 Solution: Between 6.5 and 7.5.
Water: Not more than 13.0%.
For Original Monographs of IP Indian Pharmacopoeia BP British Pharmacopoeia USP US Pharmacopoeia FCC Food Grade product, please check with the respective web-pages or books.
We manufacture and supply as under:
Chromotropic Acid Disodium Salt Dihydrate
Nitroso R-Salt or 1-Nitroso-2-naphthol-3,6-disulfonic Acid Disodium Salt.
Manufacturers:
MUBY CHEMICALS
Ambernath Mumbai, Ankleshwar Gujarat, India
TEL: (OFFICE) +912223770100, +912223726950
Current Date Time in India GMT+5:30
e-mail: info@mubychem.com
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Call toll-free 1-877-682-9243 (1-877-MUBYCHEM)
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Calcium Disodium EDTA SDS, Safety Data Sheet
MSDS Sheet, Material Safety Data Sheet 05-Oct-20
1. Product Identification
Product Name & Other Names: Calcium Disodium EDTA or Sodium Calcium Edetate
CAS Number: 62-33-9
EINECS EC Number: 200-529-9
Molecular Weight: 374.27
Chemical Formula: C10H12O8CaN2Na2-2H2O
Relevant uses and uses advised against (if any): Industrial Manufacturing.
Suppliers: As per letterhead.
2. Hazards Identification
GHS, Globally Harmonized System Classification in accordance with 29 CFR 1910
Classification according to Regulation (EC) No 1272/2008
Skin corrosion/irritation Category 2, H315
Serious eye irritation/damage Category 2A, H319
Specific target organ toxicity, single exposure; Respiratory tract irritation Category 3, H335
Labeling according GHS USA & Regulation (EC) No 1272/2008
GHS Label Elements  Irritant |
Signal Word: Warning
Hazard statements:
H315: Causes skin irritation.
H319: Causes serious eye irritation.
H335: May cause respiratory irritation.
Precautionary statements:
P261: Avoid breathing dust/fume/gas/mist/vapors/spray.
P264: Wash thoroughly after handling.
P280: Wear protective gloves/protective clothing/eye protection/face protection.
P362: Take off contaminated clothing and wash before reuse.
P302+P352 - IF ON SKIN: Wash with plenty of soap and water.
P303+P361+P353 - IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower.
P304 + P340 - IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P305 + P351 + P338 - IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P332+P313: If skin irritation occurs: Get medical advice/attention.
P337+313: If eye irritation persists get medical advice/attention.
Classification according to EU Directives 67/548/EEC or 1999/45/EC:
Hazard Symbol:
Xi = Irritant
Risk Phrases:
R36/37/38 = Irritating to eyes, respiratory system, and skin.
3. Composition/Information on Ingredients
Product Name & Other Names: Calcium Disodium EDTA.
CAS Number: 62-33-9
EINECS EC Number: 200-529-9
4. First Aid Measures
Always seek medical attention after first aid measures are provided.
Inhalation: Remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical attention.
Ingestion: Never give anything by mouth to an unconscious person. Get medical attention.
Skin Contact: Wipe off excess material from skin then immediately flush skin with plenty of water for at least 15 minutes. Remove contaminated clothing and shoes. Get medical attention. Wash clothing before reuse. Thoroughly clean shoes before reuse.
Eye Contact: Immediately flush eyes with plenty of water for at least 15 minutes, lifting lower and upper eyelids occasionally. Get medical attention immediately.
5. Fire Fighting Measures
Flammability of the Product: May be combustible at high temperature.
Products of Combustion: Fumes, Calcium Oxide, Carbon dioxide & Carbon Monoxide and Nitrogen Oxides.
Fire: Slightly flammable on heating.
Explosion: Slightly explosive on heating.
Fire Extinguishing Media: Use means suitable for extinguishing surrounding fire. Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
Special Information: In the event of a fire, wear full protective clothing and NIOSH-approved self-contained breathing apparatus with full face piece operated in the pressure demand or other positive pressure mode. At high temperatures or when moistened under fire conditions, it may produce toxic or irritating fumes. Containers may explode on heating.
6. Accidental Release Measures
Personal precautions, protective equipment, and emergency procedures: Avoid breathing dust/fumes/gas/mist/vapors/spray. Use individual protective equipment (waterproof boots, suitable protective clothing, safety glasses, etc.). Restrict unprotected personnel from the area. Prevent any contact with hot surfaces. Do not approach facing the wind. Do not touch the spilled material.
Environmental precautions: Do not let the product enter drains, soil, or water sources.
Methods and materials used for containment Cleanup procedures and Storage:
Small Spill: Avoid dust formation. Avoid breathing dust. Ensure adequate ventilation. Use appropriate tools to put the spilled solid in a convenient waste disposal container. Finish cleaning by spreading water on the contaminated surface and dispose of according to local and regional authority requirements.
Large Spill: Contain spilled material. Avoid touching the spilled material. Do not let the product enter drains. Use a shovel to put the material into a convenient waste disposal container. Finish cleaning by spreading water on the contaminated surface and dispose of according to local and regional authority requirements.
7. Handling and Storage
Precautions for safe handling: Apply according to good manufacturing and industrial hygiene practices. Ensure proper ventilation. In case of insufficient ventilation, wear suitable respiratory equipment. Wash thoroughly after handling. Do not drink, eat, or smoke while handling. Avoid contact with skin, eyes, and clothing. Minimize dust generation. Avoid breathing dust/fumes/gas/mist/vapors/spray. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation. Use individual protective equipment (waterproof boots, suitable protective clothing, safety glasses, etc.). Prevent any contact with hot surfaces.
Conditions for safe storage, including any incompatibilities: Store in cool, dry, and ventilated area away from heat sources and protected from sunlight in tightly closed original container. Keep air contact to a minimum. Do not leave the material container open. Store protected from heat, sparks and ignition sources and incompatible materials. Avoid contact with skin and eyes. Avoid inhalation of dust/mist/vapor. Do not store with incompatible materials like strong oxidizing agents.
8. Exposure Controls/Personal Protection
Airborne Exposure Limits: Not Specified.
Ventilation System: A system of local and/or general exhaust is recommended to keep employee exposures as low as possible. Local exhaust ventilation is generally preferred because it can control the emissions of the contaminant at its source, preventing dispersion of it into the general work area.
Personal Respirators (NIOSH Approved): For conditions of use where exposure to dust or mist is apparent and engineering controls are not feasible, a particulate respirator may be worn. For emergencies or instances where the exposure levels are not known, use a full-face positive-pressure, air-supplied respirator.
Skin Protection: Wear protective gloves and clean body-covering clothing.
Eye Protection: Use chemical safety goggles and/or full face shield where dusting or splashing of solutions is possible. Maintain eye wash fountain and quick-drench facilities in work area.
Other Control Measures: Maintain good housekeeping in work area. Dust deposits on floors and other surfaces may pick up moisture and cause the surfaces to become slippery and present safety hazards. Handle in accordance with good industrial hygiene and safety practice. Wash hands after handling.
9. Physical and Chemical Properties
Appearance: Colorless white powder or crystals.
Odor: Not available.
Odor threshold: Not available.
Taste; Saline
pH: Not available.
Relative density: Not available.
Melting Point: 85C
Initial boiling point and boiling range: Not available.
Flash point: Not available.
Auto-ignition temperature: Not available.
Decomposition temperature: Not available.
Upper/lower flammability or explosive limits: Not available.
Vapor pressure: Not available.
Vapor density: Not available.
Evaporation rate: Not available.
Flammability (solid, gas): Not available.
Partition coefficient: n-octanol/water: Not available.
Solubility: It is soluble in water.
Viscosity: Not available.
Molecular Weight: 374.27
Chemical Formula: C10H12O8CaN2Na2-2H2O
10. Stability and Reactivity
Stability: Stable under ordinary conditions of use and storage.
Hazardous Decomposition Products: It emits Fumes, Calcium Oxide, Carbon dioxide & Carbon Monoxide and Nitrogen Oxides.
Hazardous Polymerization: Will not occur.
Incompatibilities: Strong oxidizing agents.
Conditions to Avoid: Incompatibles and heat.
11. Toxicological Information
Acute toxicity: Harmful if inhaled. Irritating to skin and eyes.
Toxicity data:
LD50 Oral - Rat - >2000 mg/kg
LC50 Inhalation - Rat - 7 h - > 1.13 mg/l
Carcinogenic Effects: No component of this product present at levels greater than or equal to 0.1% is identified as probable, possible or confirmed human carcinogen by IARC.
Mutagenic Effects: NA
Teratogenic Effects: NA
Developmental Toxicity: NA.
12. Ecological Information
Toxicity to fish: static test LC50 - Lepomis macrochirus (Bluegill sunfish) - 2.340 mg/l - 96 hr.
Environmental Fate: Not regarded as dangerous for the environment. However, large or frequent spills may have hazardous effects on the environment.
BOD5 and COD: Not available.
Persistence and Degradability: No information available.
Mobility: No information available.
Bioaccumulation/ Accumulation: No information available.
Results of PBT and vPvB assessment: No data available for assessment.
13. Disposal Considerations
Whatever cannot be saved for recovery or recycling should be managed in an appropriate and approved waste disposal facility. Processing use or contamination of this product may change the waste management options. State and local disposal regulations may differ from federal disposal regulations. Dispose of container and unused contents in accordance with federal, state, and local requirements.
14. Transport Information
DOT USA & ADR/RID Europe: Not regulated.
Canada TDG Classification: Not regulated.
IATA: Not regulated.
15. Regulatory Information
USA:
California Prop. 65 Components: This product does not contain any chemicals known to State of California to cause cancer, birth defects, or any other reproductive harm.
Section 16 - Additional Information
European Labeling in Accordance with EC Directives:
H315: Causes skin irritation.
H319: Causes serious eye irritation.
H335: May cause respiratory irritation.
Hazard Symbol:
Xi = Irritant
Risk Phrases:
R36/37/38 = Irritating to eyes, respiratory system, and skin.
Disclaimer:
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Our company provides this MSDS sheet in good faith but makes no representation as to its comprehensiveness or accuracy. This SDS sheet is intended only as a guide to the appropriate precautionary handling of the material by a properly trained person using this product. The above information has been compiled from various sources and has the possibility of discrepancy and being out-dated information. Individuals receiving the information must exercise their independent judgment and do further search in determining its appropriateness for a particular purpose. In no case shall our company be liable to loss or damages by the product user.
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