Muby Chemicals of Mubychem Group, established in 1976, is the original manufacturers of Specialty Chemicals, Pharmaceutical Excipient, Fragrance & Flavor chemicals, Shale Gas Fracturing Chemicals in India. Mubychem Group has several manufacturing facilities spread across Western India and world wide contacts and toll manufacturers. We are exporting globally to countries like USA, Canada, Europe, UAE, South Africa, Tanzania, Kenya, Egypt, Nigeria, Cameroon, Uganda, Turkey, Mexico, Brazil, Chile, Argentina, Dubai, Korea, Vietnam, Thailand, Malaysia, Indonesia, Australia, China, Germany, France, Italy, Portugal etc. The products are offered as per required specifications and in correct shape and size in mm or meshs or microns as specified by the buyer.
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Carbasalate calcium BP & Pure Grade Manufacturers, SDS GHS MSDS Sheet

Carbasalate calcium: CAS Number: 5749-67-7, EINECS EC Number: 227-273-0, Molecular Formula: C19-H18-Ca-N2-O9, Molecular Weight: 458.4 HS Code ---**

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SDS MSDS Sheet of Carbasalate calcium Manufacturers

Carbasalate calcium
Pure & BP Grade
Carbasalate calcium

Carbasalate calcium is an analgesic, antipyretic, and anti-inflammatory drug, as well as a platelet aggregation inhibitor. It is a chelate of calcium acetylsalicylate (the calcium salt of aspirin) and urea.

Carbasalate Calcium BP Grade
Ph Eur
C19H18CaN2O9 -- 458.4 -- 5749-67-7
Action and use: Salicylate; non-selective cyclo-oxygenase inhibitor; antipyretic; analgesic; anti-inflammatory.

DEFINITION
Equimolecular compound of calcium di[2-(acetyloxy)benzoate] and urea.
Content: 99.0 per cent to 101.0 per cent (anhydrous substance).

CHARACTERS
Appearance: White or almost white, crystalline powder.
Solubility: Freely soluble in water and in dimethylformamide, practically insoluble in acetone and in anhydrous methanol.
Protect the substance from moisture during handling. Examination in aqueous solutions has to be performed immediately after preparation.

IDENTIFICATION
First identification: B, E.
Second identification: A, C, D, E.
A. Ultraviolet and visible absorption spectrophotometry.
Test solution: Dissolve 0.250 g in water and dilute to 100.0 ml with the same solvent. To 1.0 ml of the solution add 75 ml of water and 5 ml of dilute hydrochloric acid, mix and dilute to 100.0 ml with water. Examine immediately.
Spectral range: 220-350 nm.
Absorption maxima: At 228 nm and 276 nm.
Specific absorbances at the absorption maxima:
at 228 nm: 363 to 379,
at 276 nm: 49 to 53.
B. Infrared absorption spectrophotometry. Comparison: Ph. Eur. reference spectrum of carbasalate calcium.
C. Dissolve 0.1 g in 10 ml of water, boil for 2 min and cool. The solution gives reaction (a) of salicylates.
D. Heat 0.2 g with 0.2 g of sodium hydroxide; a yellow or yellowish-brown colour is produced and the vapour turns red litmus paper blue.
E. It gives reaction (a) of calcium.

TESTS
Appearance of solution: The solution is not more opalescent than reference suspension II and is colourless.
Dissolve 2.5 g in 50 ml of water.
Related substances: Maximum 0.1 per cent, expressed as acetylsalicylsalicylic acid.
In a 100 ml volumetric flask, dissolve 0.150 g in 10 ml of 0.1 M tetrabutylammonium hydroxide in 2-propanol . Allow to stand for 10 min shaking occasionally. Add 8.0 ml of 0.1 M hydrochloric acid and 20.0 ml of a 19 g/l solution of disodium tetraborate and mix. While swirling continuously, add 2.0 ml of a 10 g/l solution of aminopyrazolone and 2.0 ml of a 10 g/l solution of potassium ferricyanide. Allow to stand for 2 min, dilute to 100.0 ml with water, mix and allow to stand for 20 min. Measure the absorbance of the solution at the absorption maximum at 505 nm using water as the compensation liquid. The absorbance is not greater than 0.125.
Impurity C: Maximum 0.5 per cent.
In a 100 ml volumetric flask, dissolve 0.200 g in 80 ml of water and add 10 ml of a 10 g/l solution of ferric nitrate in a 80 g/l solution of dilute nitric acid. Dilute to 100.0 ml with water. Immediately after preparation, measure the absorbance of the solution at the absorption maximum of 525 nm using water as the compensation liquid. The absorbance is not greater than 0.115.
Sodium: Maximum 0.10 per cent.
Heavy metals: Maximum 10 ppm.
Water: Maximum 0.1 per cent, determined on 1.000 g. Use a mixture of 15 ml of anhydrous methanol and 15 ml of dimethylformamide as the solvent.

ASSAY
In a flask with a ground-glass stopper, dissolve 0.400 g in 25 ml of water. Add 25.0 ml of 0.1 M sodium hydroxide . Close the flask and allow to stand for 2 h. Titrate the excess of alkali with 0.1 M hydrochloric acid , using 0.2 ml of phenolphthalein solution. Carry out a blank titration. 1 ml of 0.1 M sodium hydroxide is equivalent to 22.92 mg of C19H18CaN2O9.

STORAGE
In an airtight container .

IMPURITIES
Specified impurities: A, B, C.
A. 2-(acetyloxy)benzoic anhydride,
B. 2-[[2-(acetyloxy)benzoyl]oxy]benzoic acid (acetylsalicylsalicylic acid),
C. 2-hydroxybenzoic acid (salicylic acid).

For Original Monographs of IP Indian Pharmacopoeia BP British Pharmacopoeia USP US Pharmacopoeia FCC Food Grade product, please check with the respective web-pages or books.

Manufacturers:

MUBY CHEMICALS
Ambernath Mumbai, Ankleshwar Gujarat, India
TEL: (OFFICE) 91-22-23770100, 23726950
Current Date Time in India GMT+5:30

e-mail: info@mubychem.com

USA & Canadian Customers may
e-mail: usa@mubychem.com
Call toll-free 1-844-682-9243 (1-844-MUBYCHEM)

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Last : 16 May, 2017

List of All the IP BP USP FCC ACS Grades of Chemicals
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Borax; Sodium Borate Boric Acid
Calcium Acetate Calcium Chloride
Calcium Gluconate Calcium Hydroxide
Calcium Lactate Calcium Oxide
Calcium Saccharate Calcium Sulfate
Chromic Chloride Citric Acid
Calcium Citrate Copper Gluconate
Copper Sulfate, Cupric Sulphate Cupric Chloride
Ferrous Fumarate Ferrous Gluconate
Fumaric Acid Ferrous Sulphate
Ferric Sulfate Ferric Ammonium Citrate
Ferric Chloride  
Gentian Violet Mannitol
Magnesium Chloride Magnesium Gluconate
Magnesium Lactate Dihydrate Magnesium Sulfate
Magnesium Trisilicate Maleic Acid
Malic Acid BP USP Manganese Gluconate
Manganese Sulfate Manganese Chloride
Methylene Blue Potassium Bromide
Potassium Chloride Potassium Gluconate
Potassium Bitartrate, Cream of Tartar Potassium Hydroxide
Potassium Iodide Potassium Iodate
Potassium Sorbate Sodium Acetate
Sodium Bicarbonate Sodium Butyrate
Sodium Caprylate Sodium Fluoride
Sodium Gluconate Sodium Hydroxide Pellets
Sodium Iodide Sodium Lactate
Sodium Perborate Sodium Propionate
Sodium Thiosulfate Sodium Sulfate
Stannous Chloride Dihydrate Zinc Carbonate
Zinc Chloride Zinc Gluconate
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Carbasalate Calcium SDS MSDS Sheet, Material Safety Data Sheet

Section 1: Chemical Product and Identification

Product Name: Carbasalate Calcium
CAS#: 5749-67-7
EINECS EC-No.: 227-273-0
Chemical Formula: C19-H18-Ca-N2-O9
Intended Use: Laboratory and Industrial Manufacturing.
SUPPLIER: As per letterhead.

Section 2: Hazards Identification

GHS, Globally Harmonized System Classification in accordance with 29 CFR 1910
Classification according to Regulation (EC) No 1272/2008 and
according to Directive 67/548/EEC.

No data available.

Labeling according to GHS & Regulation (EC) No 1272/2008

GHS Label Elements
No data available.

Signal Word: No data available.

Hazards not otherwise classified (HNOC) but perceived:
It is expected to be harmful if swallowed.
It is expected to be cause skin irritation.
It is expected to be cause serious eye irritation.
It is expected to be cause respiratory irritation.

Precautionary statements:
P261: Avoid breathing dust/fume/gas/mist/vapors/spray.
P264: Wash … thoroughly after handling.
P270: Do not eat, drink or smoke when using this product.
P280: Wear protective gloves/protective clothing/eye protection/face protection.
P330: Rinse mouth.
P362: Take off contaminated clothing and wash before reuse.
P301+312: IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell.
P302+P352 - IF ON SKIN: Wash with plenty of soap and water.
P303+P361+P353 - IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower.
P332+313: If skin irritation occurs: Get medical advice/attention.
P304 + P340 - IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P305 + P351 + P338 - IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P337+313: If eye irritation persists get medical advice/attention.
P501: Dispose of contents/container to authorized agents only.

Section 3: Composition and Information on Ingredients

Composition: Carbasalate Calcium
CAS#: 5749-67-7
EINECS EC-No.: 227-273-0
% by Weight: 100

Section 4: First Aid Measures

Always seek medical attention after first aid measures are provided.

Eye Contact: In case of contact, immediately flush eyes with plenty of water for at least 15 minutes. Get medical attention.
Skin Contact: In case of contact, immediately flush skin with plenty of water. Cover the irritated skin with an emollient. Thoroughly clean shoes and clothes before reuse. Get medical attention.
Inhalation: If Carbasalate Calcium is inhaled, remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical attention.
Ingestion: Do NOT induce vomiting unless directed to do so by medical personnel. Never give anything by mouth to an unconscious person. If large quantities of this material are swallowed, call a physician immediately.

Section 5: Fire and Explosion Data

Flammability of the Product: Carbasalate Calcium may be combustible at high temperature.
Auto-Ignition Temperature: Not available.
Products of Combustion: Some metallic oxides NO NO2 CO CO2 and fumes.
Fire Hazards in Presence of Various Substances: Slightly flammable in presence of heat. Non-flammable in presence of shocks.
Explosion Hazards in Presence of Various Substances: Slightly explosive in presence of open flames and sparks. Non-explosive in presence of shocks.
Fire Fighting Media and Instructions:
Small Fire: Use DRY chemical powder.
Large Fire: Use water spray, fog or foam. Avoid water jet.

Section 6: Accidental Release Measures

Small Spill: Avoid dust formation. Avoid breathing vapors, mist or gas. Use appropriate tools to put the spilled solid in a convenient waste disposal container. Finish cleaning by spreading water on the contaminated surface and dispose of according to legal authority requirements.
Large Spill: Use a shovel to put the material into a convenient waste disposal container. Finish cleaning by spreading water on the contaminated surface and allow drain.

Section 7: Handling and Storage

Precautions: Keep away from heat. Keep away from sources of ignition. Do not breathe dust.
Storage: Keep Carbasalate Calcium container tightly closed. Keep container in a cool, well-ventilated area.

Section 8: Exposure Controls/Personal Protection

Exposure Limits: Not established.
Engineering Controls:
Use process enclosures, local exhaust ventilation, or other engineering controls to keep airborne levels below recommended exposure limits. If user operations generate dust, fume or mist, use ventilation to keep exposure to airborne contaminants below the exposure limit.
Personal Protection: Safety glasses. Lab coat. Dust respirator. Be sure to use an approved/certified respirator or equivalent. Gloves.
Exposure Limits: Not available.

Section 9: Physical and Chemical Properties

Physical state and appearance: Carbasalate Calcium is white solid.
Odor: Not available.
Taste: Not available.
Chemical Formula: C19-H18-Ca-N2-O9
Molecular Weight: 458.4
pH (1% soln/water): Not available.
Melting Point: Not available.
Boiling Point: 321.4C
Solubility: Not available.

Section 10: Stability and Reactivity Data

Stability: It is stable.
Conditions of Instability: Excessive heat, dust generation
Incompatibility with various substances: Oxidizing Agents, heat and sunlight.
Special Remarks on Reactivity: Decomposes on heating.
Hazardous decomposition products formed under fire conditions: Nitrogen and Carbon oxides, Calcium oxide.
Polymerization: Will not occur.

Section 11: Toxicological Information

Toxicity to Animals: Not available.
Carcinogenicity
: No component of this product present at levels greater than or equal to 0.1% is identified as probable or confirmed human carcinogen by IARC, ACGIH, OSHA and NTP.
Mutagenic Effects: Not available.
Teratogenic Effects: Not available.
Environmental Toxicity: Not available.

Section 12: Ecological Information

Ecotoxicity: Not available.
Products of Biodegradation: Possibly hazardous short term degradation products are not likely. However, long term degradation products may arise.
Toxicity of the Products of Biodegradation: The product itself and its products of degradation are not toxic.

Section 13: Disposal Considerations

Waste Disposal: Waste must be disposed of in accordance legal regulations.

Section 14: Transport Information

DOT (US): Not dangerous goods
ADR/RID: Not dangerous goods
TDG/IMDG: Not dangerous goods
IATA: Not dangerous goods

Section 15: Other Regulatory Information

USA:
HMIS (Perceived): Health Hazard: 1; Fire Hazard: 1; Reactivity: 0.
NFPA (Perceived): Health: 1; Flammability: 1; Reactivity: 0.

Canada WHMIS: Not controlled under WHMIS (Canada).

EINECS EC-No.: 227-273-0

Section 16 - Additional Information

DISCLAIMER: The information and recommendations set forth herein (hereinafter "Information") are presented in good faith and believed correct as of the date hereof. It is compiled from various sources and it is not necessarily all inclusive nor fully adequate in every circumstance. In addition, these suggestions should not be confused with nor followed in violation of applicable laws, regulations, rules or insurance requirements applicable. This MSDS sheet is intended only as a guide to the appropriate precautionary handling of the material by a properly trained person using this product. Individuals receiving the information must exercise their independent judgment in determining its appropriateness for a particular purpose.