Neomycin Sulfate or Neomycin Sulphate or NMS USP BP Ph Eur Grade Manufacturers, with SDS GHS MSDS Sheet

Supplier, Manufacturer, Exporter of Neomycin Sulfate or Neomycin Sulphate or NMS, Muby Chemicals of Mubychem Group, established in 1976, is the original manufacturers of Specialty Chemicals, Pharmaceutical Excipient, Fragrance Food & Flavor chemicals, Reagent Grade Chemicals, Shale Gas Fracturing Chemicals in India. Mubychem Group has several manufacturing facilities spread across Western India and world wide contacts and toll manufacturers. We are exporting globally to countries like USA, Canada, Europe, UAE, South Africa, Tanzania, Kenya, Egypt, Nigeria, Cameroon, Uganda, Turkey, Mexico, Brazil, Chile, Argentina, Dubai, Korea, Vietnam, Thailand, Malaysia, Indonesia, Australia, China, Germany, France, Italy, Portugal etc.

The products are offered as per required specifications and in correct shape and size in mm or meshs or microns as specified by the buyer.

The participating units have one or more accreditations like FDA - cGMP and GLP approval, ISO-9001 Certified, "REACH" Registered, ISO-14001, ISO/IEC 17025, ISO-22000, FSSC 22000, ISO 45001, Kosher Certified, Halal Certified, HACCP, FSSAI. We offer Commercial Pure & IP BP EP Ph Eur USP NF JP FCC Food Grade Analytical Reagent Grades of Chemicals

Bookmark this Web Site -- or -- Email This Page Info to a Colleague or Yourself

Search our website here:

---------

Export to USA UAE Europe Africa Tanzania Kenya Egypt Turkey Jumbo Packing; Exports to USA UAE Europe Africa Tanzania Kenya Uganda Egypt Turkey Brazil Chile Argentina Dubai etc. Packing Palletized and Shrink Wrapped; 25kg or 50kg or 55 lbs HDPE laminated bags with an extra HMHDP liner Drum Packing for better transportation Drum Packing & Palletized Liquid Chemical Export Import Air Freighting

Neomycin Sulfate or Neomycin Sulphate or NMS CAS Number 1405-10-3, EINECS EC Number: 215-773-1, Molecular Formula: C23H46N6O13-3H2SO4, Molecular Weight: 908.90, HS Code 29419050

Specifications, Safety Data Sheet, Manufacturing process details, Wholesale retail buy sell prices, Uses etc available on line in these pages for Neomycin Sulfate or Neomycin Sulphate or NMS.

Neomycin sulfate is an aminoglycoside antibiotic and calcium channel protein inhibitor. Neomycin sulfate also binds to prokaryotic ribosomes inhibiting translation and is effective against gram-positive and gram-negative bacteria.

General Properties and Specifications of Neomycin Sulfate or Neomycin Sulphate or NMS:
Appearance: Cream white to yellowish white powder.
Solubility of 10% aq. solution: Clear, slight yellow.
Potency: 600 minimum μg/mg or as agreed.
pH: 5.0 - 7.5 5% aq. solution.
Specific rotation [α]: +53° to +59° (C=10 ,Water)
Solubility: Soluble in water.
Storage: 2C to 8C (Refrigerate). OK to freeze. Protect from light. Protect from moisture.

Neomycin Sulfate USP Grade Specifications:
Neomycin sulfate.
Neomycins sulfate CAS 1405-10-3
UNII: 057Y626693
UNII: I16QD7X297

Neomycin Sulfate is the sulfate salt of a kind of neomycin, an antibacterial substance produced by the growth of Streptomyces fradiae aksman (Fam. Streptomycetaceae), or a mixture of two or more such salts. It has a potency equivalent to not less than 600 µg of neomycin per mg, calculated on the dried basis.
Packaging and storage: Preserve in tight, light-resistant containers.

Identification:
A: It meets the requirements for neomycin under Thin-Layer Chromatographic Identification Test.
B: Dissolve about 10 mg in 1 mL of water, add 5 mL of 15 N sulfuric acid, and heat at 100C for 100 minutes. Allow to cool, add 10 mL of xylene, and shake for 10 minutes. Allow to separate and decant the xylene layer. To the xylene layer add 10 mL of p-bromoaniline TS, and shake: a vivid pink-red color develops upon standing.
C: A solution (1 in 20) responds to the tests for Sulfate.

pH: between 5.0 and 7.5, in a solution containing 33 mg of neomycin per mL.
Loss on drying: Dry about 100 mg in vacuum at a pressure not exceeding 5 mm of mercury at 60C for 3 hours: it loses not more than 8.0% of its weight.
Other requirements: Where the label states that Neomycin Sulfate is sterile, it meets the requirements for Sterility and Bacterial endotoxins under Neomycin for Injection.

Neomycin Sulfate BP Ph Eur Grade:
Neomycin Sulphate
C23H46N6O13,xH2SO4 --- 615 (base)

DEFINITION
Mixture of sulfates of substances produced by the growth of certain selected strains of Streptomyces fradiae, the main component being the sulfate of 2-deoxy-4-O-(2,6-diamino-2,6-dideoxy-α-D-glucopyranosyl)-5-O-[3-O-(2,6-diamino-2,6-dideoxy-β-L-idopyranosyl)-β-D-ribofuranosyl]-D-streptamine (neomycin B).
Content: Minimum of 680 IU/mg (dried substance).

CHARACTERS
Appearance: White or yellowish-white powder, hygroscopic.
Solubility: Very soluble in water, very slightly soluble in alcohol, practically insoluble in acetone.

IDENTIFICATION
A. Examine the chromatograms obtained in the test for related substances.
B. It gives reaction (a) of sulfates.

For Original Monographs of IP Indian Pharmacopoeia BP British Pharmacopoeia USP US Pharmacopoeia FCC Food Grade product, please check with the respective web-pages or books.

MUBY CHEMICALS
Ambernath Mumbai, Ankleshwar Gujarat, India
TEL: (OFFICE) +912223770100, +912223726950
Current Date Time in India GMT+5:30

USA, Canada, Mexico and other American
neighbouring buyers may
e-mail: us@mubychem.com
Call toll-free 1-877-682-9243 (1-877-MUBYCHEM)

Exporters to USA Canada UAE Europe South Africa Tanzania Kenya Uganda Egypt Nigeria Turkey Mexico Brazil Argentina Chile Dubai etc.

Global or International Suppliers, Exporters, Importers, Manufacturers

I shall pass through this world, but once. If therefore, there is any good that I can do, or if there is any favor that I can show to a fellow human being, let me do it now. Let me not defer or neglect it. For I shall not tread this way again

Neomycin Sulfate or Neomycin Sulphate or NMS SDS or Safety Data Sheet
Material Safety Data Sheet 12-Dec-23

Product Name & Other Names: Neomycin Sulfate or Neomycin Sulphate or NMS.
CAS No.: 1405-10-3
EINECS EC Number: 215-773-1
Molecular Formula: C23H46N6O13-3H2SO4
Molecular Weight: 908.90
Relevant uses and uses advised against (if any): Industrial use only.
Supplier: As per letterhead.

GHS, Globally Harmonized System Classification in accordance with 29 CFR 1910
Classification according to Regulation (EC) No 1272/2008

Skin sensitization, Category 1, H317
Sensitization, respiratory Category 1 - H334

Hazard statements
H317 May cause an allergic skin reaction.
H334 - May cause allergy or asthma symptoms or breathing difficulties if inhaled.

Precautionary statements Prevention
P261 -Avoid breathing dust/fumes.
P271 -Use only outdoors or in a well-ventilated area.
P285: In case of inadequate ventilation wear respiratory protection.
P280 -Wear protective gloves/protective clothing/eye protection/face protection.
Precautionary statements Response
P304+341: IF INHALED: If breathing is difficult, remove victim to fresh air and keep at rest in a position comfortable for breathing.
P305+P351+P338- IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P337+P313- If eye irritation persists: Get medical advice/attention.
P302+P352 -IF ON SKIN: Wash with plenty of water and soap.
P332+P313 -If skin irritation occurs: Get medical advice/attention.
Precautionary statements Storage
P405 Store locked up.
P403+P233 Store in a well-ventilated place. Keep container tightly closed.
Precautionary statements Disposal
P501 Dispose of contents/container in accordance with local regulations.

Classification according to EU Directives 67/548/EEC or 1999/45/EC:
Hazard Symbol:
Xn = Harmful
Risk Phrases:
R43 = May cause sensitization by skin contact.
R42 May cause sensitization by inhalation.

Product Name & Other Names: Neomycin Sulfate or Neomycin Sulphate or NMS.
CAS No.: 1405-10-3
EINECS EC Number: 215-773-1

Eye Contact: Wash out immediately with fresh running water. Ensure complete irrigation of the eye by keeping eyelids apart and away from eye and moving the eyelids by occasionally lifting the upper and lower lids. Seek medical attention without delay; if pain persists or recurs seek medical attention. Removal of contact lenses after an eye injury should only be undertaken by skilled personnel.
Skin Contact: Immediately remove all contaminated clothing, including footwear. Flush skin and hair with running water (and soap if available). Seek medical attention in event of irritation.
Inhalation: Lay patient down. Keep warm and in rest. Prostheses such as false teeth, which may block airway, should be removed, where possible, prior to initiating first aid procedures. Apply artificial respiration if not breathing, preferably with a demand valve resuscitator, bag-valve mask device, or pocket mask as trained. Perform CPR if necessary. Transport to hospital, or doctor, without delay.
Ingestion: If swallowed do NOT induce vomiting. If vomiting occurs, lean patient forward or place on left side (head-down position, if possible) to maintain open airway and prevent aspiration. Observe the patient carefully. Never give liquid to a person showing signs of being sleepy or with reduced awareness i.e., becoming unconscious. Give water to rinse out mouth, then provide liquid slowly and as much as casualty can comfortably drink. Seek medical advice.
Indication of any medical attention and special treatment needed: Treat symptomatically.

Extinguishing media: Water spray or fog, Foam, Dry chemical powder, Carbon dioxide.
Fire Fighting: Alert Fire Brigade and tell them location and nature of hazard. Wear breathing apparatus plus protective gloves. Prevent, by any means available, spillage from entering drains or water courses. Use water delivered as a fine spray to control fire and cool adjacent area. DO NOT approach containers suspected to be hot. Cool fire exposed containers with water spray from a protected location. If safe to do so, remove containers from path of fire.
Fire/Explosion Hazard: Combustible solid which burns; it is estimated that most organic dusts are combustible - according to the circumstances under which the combustion process occurs, such materials may cause fires and / or dust explosions. Avoid generating dust, particularly clouds of dust in a confined or unventilated space as dusts may form an explosive mixture with air, and any source of ignition, i.e., flame or spark, will cause fire or explosion.
Combustion products: Carbon monoxide (CO), carbon dioxide (CO2), sulfur oxides, and nitrogen compounds. May emit poisonous and corrosive fumes.
Special Information: In the event of a fire, wear full protective clothing and NIOSH-approved self-contained breathing apparatus with full face piece operated in the pressure demand or other positive pressure mode. At high temperatures under fire conditions, it may produce toxic or irritating fumes. Fire-extinguishing work is done from the windward and a suitable fire-extinguishing method according to the surrounding situation is used. Uninvolved persons should evacuate to a safe place.

Personal precautions, protective equipment, and emergency procedures: Avoid breathing dust/fumes/gas/mist/vapors/spray. Ensure adequate ventilation. Use individual protective equipment (waterproof boots, suitable protective clothing, safety glasses, etc.). Restrict unprotected personnel from the area. Prevent any contact with hot surfaces. Do not approach facing the wind. Do not touch the spilled material.
Environmental precautions: Do not let the product enter drains, soil, or water sources.
Methods and materials used for containment cleanup procedures and Storage:
Minor Spills: Remove all ignition sources. Clean up all spills immediately. Avoid contact with skin and eyes. Control personal contact with the substance, by using protective equipment. Use dry clean up procedures and avoid generating dust. Place in a suitable, labeled container for waste disposal.
Major Spills: Alert Emergency Services and tell them location and nature of hazard. Control personal contact by wearing protective clothing. Recover product wherever possible. Contain spilled material. Cover with an inert, non-combustible absorbent material, (e.g., sand, earth, diatomaceous earth, vermiculite).
IF DRY: Use dry clean up procedures and avoid generating dust. Collect residues and place in sealed plastic bags or other containers for disposal.
IF WET: Vacuum/shovel up and place in labelled containers for disposal.
ALWAYS: Wash area with water and prevent runoff into drains.

Precautions for safe handling: Apply according to good manufacturing and industrial hygiene practices. Ensure proper ventilation. Wash thoroughly after handling. Do not drink, eat, or smoke while handling. Minimize dust generation. Avoid breathing dust/fumes/gas/mist/vapors/spray. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation. Use individual protective equipment (waterproof boots, suitable protective clothing, safety glasses, etc.). Prevent any contact with hot surfaces.
Conditions for safe storage, including any incompatibilities: Store in cool, dry, and ventilated area away from heat sources and protected from sunlight in tightly closed original container. Keep air contact to a minimum. Do not leave the material container open. Avoid contact with skin and eyes. Avoid inhalation of dust/mist/vapor. Store protected from heat, sparks and ignition sources and incompatible materials like oxidizers. Storage: 2C to 8C (Refrigerate). OK to freeze. Protect from light. Protect from moisture.

Airborne Exposure Limits: This product does not contain any hazardous materials with occupational exposure limits established by the region-specific regulatory bodies.
Ventilation System: A system of local and/or general exhaust is recommended to keep employee exposures below the Airborne Exposure Limits. Local exhaust ventilation is generally preferred because it can control the emissions of the contaminant at its source, preventing dispersion of it into the general work area. Please refer to the ACGIH document, Industrial Ventilation, A Manual of Recommended Practices, most recent edition, for details.
Personal Respirators (NIOSH Approved): If the exposure limit is exceeded, a full-face piece respirator with dust/mist filter may be worn. For emergencies or instances where the exposure levels are not known, use a full-face piece positive-pressure, air-supplied respirator. WARNING: Air purifying respirators do not protect workers in oxygen-deficient atmospheres.
Skin Protection: Wear impervious protective clothing, including boots, gloves, lab coat, apron, or coveralls, as appropriate, to prevent skin contact.
Eye Protection: Use chemical safety goggles and/or full-face shield where dusting or splashing of solutions is possible. Maintain eye wash fountain and quick-drench facilities in work area.
Other Control Measures: Maintain good housekeeping in work area. Handle in accordance with good industrial hygiene and safety practice. Wash hands after handling.

Appearance: Cream white to yellowish white powder.
Odor: Not available.
Odor threshold: Not available.
pH: 5.0 - 7.5 5% aq. solution.
Relative density: Not available.
Melting point / freezing point (°C): Not available.
Initial boiling point and boiling range: Not available.
Flash point: Not available.
Auto-ignition temperature: Not available.
Decomposition temperature: Not available.
Upper/lower flammability or explosive limits: Not available.
Vapor pressure: Not available.
Vapor density: Not available.
Evaporation rate: Not available.
Flammability (solid, gas): Not available.
Partition coefficient: n-octanol/water: Not available.
Solubility in water (g/L): Soluble in water.
Viscosity: Not available.
Molecular Formula: C23H46N6O13-3H2SO4
Molecular Weight: 908.90

Chemical stability: Product is considered stable under recommended storage conditions. Unstable in the presence of incompatible materials.
Hazardous polymerization: Will not occur.
Conditions to avoid- Heat sparks flame moisture and incompatibilities.
Incompatible materials- Oxidizing agents
Hazardous decomposition products- Carbon monoxide (CO), carbon dioxide (CO2), sulfur oxides, and nitrogen compounds. May emit poisonous and corrosive fumes.

Toxicity to Animals: Data Not Available.
Mutagenicity: Data Not Available to make classification
Carcinogenicity: Not a reported carcinogen as per IARC, ACGIH, NTP & OSHA.
Reproductivity: Data Not Available to make classification.

DO NOT discharge into sewer or waterways.
Toxicity: No information available.
Persistence and Degradability: Unlikely to persist due to water solubility.
Mobility: Likely to be mobile due to water solubility.
Bioaccumulation/ Accumulation: No information available.
Mobility in soil: No information available.
Results of PBT and vPvB assessment: No data available for assessment.

Return empty containers to supplier for reuse/ recycling if possible. Legislation addressing waste disposal requirements may differ by country, state and/ or territory. Each user must refer to laws operating in their area. In some areas, certain wastes must be tracked. Dispose according to law.
In all cases disposal to sewer may be subject to local laws and regulations and follow the same.

DOT USA, TDG Canada & ADR/RID Europe: Not Regulated.
IMDG/IMO: Not Regulated.
IATA: Not Regulated.

SARA 311/312 Hazards: Acute Health Hazard. See section 2.
California Prop. 65 Components: This product does not contain any chemicals known to the State of California to cause cancer, birth defects, or any other reproductive harm.

European Labeling in Accordance with EC Directives:
H317 May cause an allergic skin reaction.
H335-May cause respiratory irritation.

Disclaimer:
**************************
Our company provides this MSDS sheet in good faith but makes no representation as to its comprehensiveness or accuracy. This SDS sheet is intended only as a guide to the appropriate precautionary handling of the material by a properly trained person using this product. The above information has been compiled from various sources and has the possibility of discrepancy and being out-dated information. Individuals receiving the information must exercise their independent judgment and do further search in determining its appropriateness for a particular purpose. In no case shall our company be liable to loss or damages by the product user.
**************************

List of All the IP, BP, EP, Ph Eur, USP NF, JP, FCC Food, Analytical Reagent Grades of Chemicals
Best Seller Fast Moving IP, BP, EP, Ph Eur, USP NF, JP, FCC Food, Analytical Reagent Grades of Chemicals Ex-stock Items
Aluminum Chloride Hexahydrate	Aluminium Potassium Sulphate
Ammonium Bicarbonate	Ammonium Carbonate
Ammonium Chloride	Ammonium Persulfate
Borax; Sodium Borate	Boric Acid
Calcium Chloride	Calcium Saccharate
Calcium Sulfate	Carbamide Peroxide
Chromic Chloride	Cupric or Copper Chloride
Ferric Chloride Hexahydrate	Fumaric Acid
Glacial Acetic Acid	Lactobionic Acid
Magnesium Chloride	Magnesium Sulfate
Manganese Chloride	Manganese Sulfate
Potassium Bromide	Potassium Chloride
Potassium Hydroxide Pellets	Potassium Nitrate
Propylene Carbonate	Potassium Monopersulfate
Selenious acid	Sodium Acetate
Sodium Bromate	Sodium Diacetate
Sodium Formaldehyde Bisulfite	Sodium Lactobionate
Sodium Thiosulfate	Zinc Chloride