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Bismuth Subsalicylate BP USP Grade Manufacturers, SDS GHS MSDS Sheet

Bismuth Subsalicylate: CAS Number: 14882-18-9, EINECS EC Number: 238-953-1, Molecular Formula: HOC6H4COOBiO, Molecular Weight: 362.09, HS Code ---**

For SDS MSDS Sheet Click
SDS MSDS Sheet of Bismuth Subsalicylate Manufacturers

Bismuth Subsalicylate
Pure BP USP FCC Food Grade
Bismuthsub Salicylate

Bismuth Subsalicylate BP Grade
C7H5BiO4
362.1 -- 14882-18-9
Ph Eur

DEFINITION
Complex of bismuth and salicylic acid.
Content: 56.0 per cent to 59.4 per cent of Bi (Ar 209.0) (dried substance).

CHARACTERS
Appearance: White or almost white powder.
Solubility: Practically insoluble in water and in alcohol. It dissolves in mineral acids with decomposition.

IDENTIFICATION
A. To 0.5 g add 10 ml of hydrochloric acid. Heat on a boiling water-bath for 5 min. Cool and filter. Retain the filtrate for identification test B. Wash the residue with dilute hydrochloric acid and then with water. Dissolve the residue in 0.5-1 ml of dilute sodium hydroxide solution. Add 15 ml of water. Neutralise with dilute hydrochloric acid. The solution gives reaction (a) of salicylates.
B. The filtrate obtained in identification test A gives reaction (b) of bismuth.

TESTS
Solution S: In a porcelain or quartz dish, ignite 1.0 g, increasing the temperature very gradually. Heat in a muffle furnace at 600 ± 25C for 2 h. Cool and dissolve the residue with warming in 4 ml of a mixture of equal volumes of lead-free nitric acid and water and dilute to 20 ml with water.
Acidity: Shake 2.0 g with 30 ml of ether for 1 min and filter. To the filtrate add 30 ml of alcohol and 0.1 ml of thymol blue solution. Not more than 0.35 ml of 0.1 M sodium hydroxide is required to change the colour of the indicator to blue.
Chlorides: Maximum 200 ppm.
Nitrates: Maximum 0.4 per cent.
Copper: Maximum 50.0 ppm.
Lead: Maximum 20.0 ppm.
Silver: Maximum 25.0 ppm.
Soluble bismuth: Maximum 40.0 ppm.
Loss on drying: Maximum 1.0 per cent, determined on 1.000 g by drying in an oven at 105C.

ASSAY
Dissolve with heating 0.300 g in 10 ml of a mixture of 2 volumes of perchloric acid and 5 volumes of water. To the hot solution, add 200 ml of water and 50 mg of xylenol orange triturate. Titrate with 0.1 M sodium edetate until a yellow colour is obtained.
1 ml of 0.1 M sodium edetate is equivalent to 20.90 mg of Bi.

Bismuth Subsalicylate USP Grade
C7H5BiO4 -- 362.09
(2-Hydroxybenzoato-O1)-oxobismuth.
2-Hydroxybenzoic acid bismuth (3+) salt, basic [14882-18-9].
Bismuth Subsalicylate is a basic salt that when dried at 105 for 3 hours contains not less than 56.0 percent and not more than 59.4 percent of bismuth (Bi) and not less than 36.5 percent and not more than 39.3 percent of total salicylates.

Identification:
A: Infrared Absorption.
B: It responds to the tests for Bismuth.
pH: between 2.7 and 5.0, in a solution prepared as follows. Mix 10 g of Bismuth Subsalicylate and 90 mL of water, shake by mechanical means for 10 minutes, and filter.
Loss on drying: Dry it at 105C for 3 hours: it loses not more than 1.0% of its weight.
Limit of nitrate: 0.4%.
Arsenic: The limit is 10 µg per g.
Limit of free salicylic acid: To pass the test. (Not more than 0.2%).
Limit of copper, lead, and silver: To pass the test. (40 µg per g).

For Original Monographs of IP Indian Pharmacopoeia BP British Pharmacopoeia USP US Pharmacopoeia FCC Food Grade product, please check with the respective web-pages or books.

Manufacturers:

MUBY CHEMICALS
Ambernath Mumbai, Ankleshwar Gujarat, India
TEL: (OFFICE) 91-22-23770100, 23726950
Current Date Time in India GMT+5:30

e-mail: info@mubychem.com

USA & Canadian Customers may
e-mail: usa@mubychem.com
Call toll-free 1-844-682-9243 (1-844-MUBYCHEM)

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Last : 16 May, 2017

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Sodium Gluconate Sodium Hydroxide Pellets
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Bismuth Subsalicylate SDS GHS MSDS Sheet, Material Safety Data Sheet

1. Product Identification

Synonyms: Bismuth oxysalicylate, Bismuth(III) subsalicylate, Bismuth(III) salicylate basic
CAS No.: 14882-18-9
EINECS EC Number: 238-953-1
Molecular Weight: 362.09
Chemical Formula: HOC6H4COOBiO
Relevant Uses: Industrial use only.
Supplier: As per letterhead.

2: Hazards Identification

GHS, Globally Harmonized System Classification in accordance with 29 CFR 1910
Classification according to Regulation (EC) No 1272/2008

Not a hazardous substance or mixture according to Regulation (EC) No. 1272/2008.
This substance is not classified as dangerous according to Directive 67/548/EEC.

Labeling according to GHS & Regulation (EC) No 1272/2008

GHS Label Elements
NONE

Signal Word: None

Hazards not otherwise classified (HNOC):
May causes mild skin irritation.
May causes mild eye irritation.

Precautionary statements:
P261: Avoid breathing dust/fume/gas/mist/vapors/spray.
P262: Do not get in eyes, on skin, or on clothing.
P281: Use personal protective equipment as required.
P302+P352 - IF ON SKIN: Wash with plenty of soap and water.
P303+P361+P353 - IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower.
P304 + P340 - IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P305 + P351 + P338 - IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P337+313: If eye irritation persists get medical advice/attention.

OSHA Hazards: No known OSHA hazards.

3. Composition/Information on Ingredients

Ingredient: Bismuth Subsalicylate
EINECS EC Number: 238-953-1
Molecular Weight: 362.09
Percent: 95 - 100%

4. First Aid Measures

Always seek medical advice after the first aid treatment.

SKIN: Wash exposed area with soap and water.
EYES: Wash eyes with plenty of water for at least 15 minutes, lifting lids occasionally. Seek Medical Aid.
INHALATION: Remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen.
INGESTION: If swallowed, induce vomiting immediately after giving two glasses of water. Never give anything by mouth to an unconscious person.

5. Fire Fighting Measures

Fire: It is not considered to be a fire hazard.
Explosion: Not considered to be an explosion hazard.
Fire Extinguishing Media: Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide. Use means suitable for extinguishing surrounding fire.
Special Information: In the event of a fire, wear full protective clothing and NIOSH-approved self-contained breathing apparatus with full face piece operated in the pressure demand or other positive pressure mode.

6. Accidental Release Measures

Avoid dust formation. Avoid breathing vapours, mist or gas. Ventilate area of leak or spill. Wear appropriate personal protective equipment as specified in Section 8. Spills: Sweep up and containerize for reclamation or disposal. Vacuuming or wet sweeping may be used to avoid dust dispersal.

7. Handling and Storage
Keep in a tightly closed container, stored in a cool, dry, ventilated area. Protect against physical damage. Containers of this material may be hazardous when empty since they retain product residues (dust, solids); observe all warnings and precautions listed for the product.

8. Exposure Controls/Personal Protection

Engineering Controls: Use process enclosures, local exhaust ventilation, or other engineering controls to keep airborne levels below recommended exposure limits. If user operations generate dust, fume or mist, use ventilation to keep exposure to airborne contaminants below the exposure limit.
Personal Protection: Safety glasses. Lab coat. Dust respirator. Be sure to use an approved/certified respirator or equivalent Gloves.
Personal Protection in Case of a Large Spill:
Splash goggles. Full suit. Dust respirator. Boots. Gloves. A self contained breathing apparatus should be used to avoid inhalation of the product. Suggested protective clothing might not be sufficient; consult a specialist BEFORE handling this product.
Exposure Limits:
No specific OES assigned, however for dusts of any kind, ensure LTEL (8-hour TWA ref. period) level does not exceed 10 mg.m3 for total inhalable dust or 4 mg.m3 for respirable dust (or) as recommended in current edition of EH40. Consult local authorities for acceptable exposure limits.

9. Physical and Chemical Properties

Appearance: It is fine, off-white powder.
Odor: Odorless.
Solubility: Insoluble in water.
Specific Gravity: NA.
pH: > NA.
% Volatile by volume @ 21C (70F): 0
Boiling Point: NA.
Melting Point: >350C - lit.
Molecular Weight: 362.09
Chemical Formula: HOC6H4COOBiO

10. Stability and Reactivity

Stability: It is stable under ordinary conditions of use and storage.
Hazardous Decomposition Products: When heated to decomposition, emits bismuth oxide, fumes and liberates carbon dioxide.
Hazardous Polymerization: Will not occur.
Incompatibilities: Oxidizing agents.
Conditions to Avoid: Heat, incompatibles.

11. Toxicological Information

Acute toxicity: Not available.
Carcinogenicity: No component of this product present at levels greater than or equal to 0.1% is identified as probable, possible or confirmed human carcinogen by IARC, ACGIH, OSHA and NTP.

12. Ecological Information

Environmental Fate: No information found.
Environmental Toxicity: No information found.
Results of PBT and vPvB assessment: Not available.

13. Disposal Considerations

Whatever cannot be saved for recovery or recycling should be managed in an appropriate and approved waste disposal facility. Processing, use or contamination of this product may change the waste management options. State and local disposal regulations may differ from federal disposal regulations. Dispose of container of and unused contents in accordance with federal, state and local requirements.

14. Transport Information

DOT (US): Not dangerous goods
ADR/RID: Not dangerous goods
IMDG: Not dangerous goods
IATA: Not dangerous goods

15. Regulatory Information

USA Regulations:
TSCA 8(b) inventory: Listed
OSHA Hazards: No known OSHA hazards
SARA 302: No chemicals in this material are subject to the reporting requirements of SARA Title III, Section 302.
SARA 313: This material does not contain any chemical components with known CAS numbers that exceed the threshold (De Minimis) reporting levels established by SARA Title III, Section 313.
SARA 311/312 Hazards: No SARA Hazards
CERCLA: No chemicals in this material with known CAS numbers are subject to the reporting requirements of CERCLA
California Proposition 65: This product does not contain any Proposition 65 chemicals

Canada WHMIS Hazard Class: Not controlled.

EINECS EC Number: 238-953-1

Disclaimer:
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Our company provides this MSDS sheet in good faith but makes no representation as to its comprehensiveness or accuracy. This SDS sheet is intended only as a guide to the appropriate precautionary handling of the material by a properly trained person using this product. The above information has been compiled from various sources and has the possibility of discrepancy and being out-dated information. Individuals receiving the information must exercise their independent judgment and do further search in determining its appropriateness for a particular purpose. In no case shall our company be liable to loss or damages by the product user.
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